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Validation of the role of non - invasive demographic and biochemical markers in assessment of hepatic fibrosis in Egyptian patients with chronic hepatitis C / Ahmed Abdelmonem Mohamed Cordie ; Supervised Gamal Eldin Esmat Mohamed , Ahmed Mohamed Salama , Marwa Mahmoud Alsharkawy

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Ahmed Abdelmonem Mohamed Cordie , 2015Description: 127 P. : facsimiles ; 25cmOther title:
  • تقييم الدلالات الديموغرافيه و البيوكميائيه الغير تداخلية فى تحديد نسبة التليف الكبدى فى المرضى المصريين المصابين بالالتهاب الكبدى المزمن الفيروسى - سى [Added title page title]
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Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Tropical Medicine Summary: Hepatic fibrosis is an inclusion indicator for treatment and a major independent predictor of treatment response in patients with chronic hepatitis C. Liver biopsy, considered as the 2gold standard3 for evaluating liver fibrosis, has carried some drawbacks. Currently used noninvasive predictors of fibrosis are considered less accurate than liver biopsy. To evaluate effectiveness of demographic and biochemical markers as a simple non invasive model for prediction of significant hepatic fibrosis in patients with chronic hepatitis C virus (HCV) infection and comparing its diagnostic performance to liver biopsy. Cross sectional prospective study including 200 Egyptian patients with chronic hepatitis C. Routine pre-treatment workup, special tests (Alpha 2 macroglobulin, carbohydrate 19.9 Antigen) and reference needle liver biopsy were performed. Fib - 4, Egyscore, AST to platelet ratio index (APRI), Göteborg University Cirrhosis Index (GUCI) were validated. Patients were divided into two groups, first with insignificant fibrosis (< F2), and second with significant fibrosis ({u2265}F2) using the Metavir score
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Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.33.M.Sc.2015.Ah.V (Browse shelf(Opens below)) Not for loan 01010110066849000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.33.M.Sc.2015.Ah.V (Browse shelf(Opens below)) 66849.CD Not for loan 01020110066849000
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Cai01.11.33.M.Sc.2015.Ah.N Narrow band imaging colonoscopy compared to standard white light colonoscopy in detection of different colonic lesions / Cai01.11.33.M.Sc.2015.Ah.R Relationship between hepatoduodenal lymphadenopathy and severity of chronic liver disease as well as response to antiviral therapy in Egyptian patients with chronic hepatitis c virus genotype 4 / Cai01.11.33.M.Sc.2015.Ah.R Relationship between hepatoduodenal lymphadenopathy and severity of chronic liver disease as well as response to antiviral therapy in Egyptian patients with chronic hepatitis c virus genotype 4 / Cai01.11.33.M.Sc.2015.Ah.V Validation of the role of non - invasive demographic and biochemical markers in assessment of hepatic fibrosis in Egyptian patients with chronic hepatitis C / Cai01.11.33.M.Sc.2015.Ah.V Validation of the role of non - invasive demographic and biochemical markers in assessment of hepatic fibrosis in Egyptian patients with chronic hepatitis C / Cai01.11.33.M.Sc.2015.Ge.P Prevalence and genetic background of clarithromycin resistance of helicobacter pylori strains in Egyptian patients / Cai01.11.33.M.Sc.2015.Ge.P Prevalence and genetic background of clarithromycin resistance of helicobacter pylori strains in Egyptian patients /

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Tropical Medicine

Hepatic fibrosis is an inclusion indicator for treatment and a major independent predictor of treatment response in patients with chronic hepatitis C. Liver biopsy, considered as the 2gold standard3 for evaluating liver fibrosis, has carried some drawbacks. Currently used noninvasive predictors of fibrosis are considered less accurate than liver biopsy. To evaluate effectiveness of demographic and biochemical markers as a simple non invasive model for prediction of significant hepatic fibrosis in patients with chronic hepatitis C virus (HCV) infection and comparing its diagnostic performance to liver biopsy. Cross sectional prospective study including 200 Egyptian patients with chronic hepatitis C. Routine pre-treatment workup, special tests (Alpha 2 macroglobulin, carbohydrate 19.9 Antigen) and reference needle liver biopsy were performed. Fib - 4, Egyscore, AST to platelet ratio index (APRI), Göteborg University Cirrhosis Index (GUCI) were validated. Patients were divided into two groups, first with insignificant fibrosis (< F2), and second with significant fibrosis ({u2265}F2) using the Metavir score

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