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Evaluation of Ý-lactam and aminoglycosides synergistic effect on multidrug resistant pseudomonas / Noha Salah Eldein Elsayed Ali Soliman ; Supervised Mona Abdelaziz Wassef , Maha Mohammed Gaafar , Dina Mohammed Hassan

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Noha Salah El-Dein El-Sayed Ali Soliman , 2015Description: 153 P. : charts , facsimiles ; 25cmOther title:
  • تقييم تأثير التآزر بين العقار من نوع البيتالاكتام مع الأمينوجليكوزايد على ميكروب السودوموناس [Added title page title]
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Dissertation note: Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology Summary: Multidrug resistant Pseudomonas is one of the rapidly spreading bacteria causing infections with serious outcomes due to limited therapeutic options. Rapid spread of multidrug resistant bacteria (MDR) has become an emerging threat and a matter of concern worldwide.Our work aimed to screen for carbapenem resistance in 250 isolates of MDR Pseudomonas, evaluate the synergistic effect of Ý-lactam and aminoglycoside combination by using E-test in 50 selected carbapenem resistant MDR Pseudomonas isolates and investigate the role of plasmid transfer in spread of resistance.The distribution of the MDR Pseudomonas showed that the majority were encountered from ICU (47.6%) compared to inpatient wards (43.2%). Among different samples showed that the highest prevalence were in sputum (46.8%), followed by urine (26.8%), pus (21.6%) while the samples with the lowest prevalence were blood (4%) and ear discharge (2.8%)
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Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.07.Ph.D.2015.No.E (Browse shelf(Opens below)) Not for loan 01010110067029000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.07.Ph.D.2015.No.E (Browse shelf(Opens below)) 67029.CD Not for loan 01020110067029000

Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology

Multidrug resistant Pseudomonas is one of the rapidly spreading bacteria causing infections with serious outcomes due to limited therapeutic options. Rapid spread of multidrug resistant bacteria (MDR) has become an emerging threat and a matter of concern worldwide.Our work aimed to screen for carbapenem resistance in 250 isolates of MDR Pseudomonas, evaluate the synergistic effect of Ý-lactam and aminoglycoside combination by using E-test in 50 selected carbapenem resistant MDR Pseudomonas isolates and investigate the role of plasmid transfer in spread of resistance.The distribution of the MDR Pseudomonas showed that the majority were encountered from ICU (47.6%) compared to inpatient wards (43.2%). Among different samples showed that the highest prevalence were in sputum (46.8%), followed by urine (26.8%), pus (21.6%) while the samples with the lowest prevalence were blood (4%) and ear discharge (2.8%)

Issued also as CD

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