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Biological evaluation of anti - androgenic effect of some plants / Karem Elsayed Aly Fouda ; Supervised Mohamed Magdy Rashed , Magdy Abdelaleem Shallan , Laila Hanna Mosaad

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Karem Elsayed Aly Fouda , 2015Description: 150 P. : charts , photographs ; 25cmOther title:
  • التقييم الحيوى للتأثير المضاد لهرمون الأندروجين لبعض النباتات [Added title page title]
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  • Issued also as CD
Dissertation note: Thesis (Ph.D.) - Cairo University - Faculty of Agriculture - Department of Agricultural Biochemistry Summary: The present study was designed to evaluate the anti-androgenic effect of some plants in castrated rats (flaxseed, sesame seeds, safflower seeds and soybean seeds) which were analyzed then petroleum ether and ethanol extracts were prepared from these samples. Some phytochemicals such as total phenolic compounds content, fatty acids, hydrocarbons and phytosterols contents were determined in all the studied plants. Also the anti - cancer effect of all the plants powder under investigation were studied against prostate cancer using cell-line technique. In the first experiment of the present study flax, sesame, safflower and soybean seeds were evaluated as anti-androgenic agents in castrated/testosterone rats in form of petroleum ether, ethanol extracts and whole powder. The nutritional safety of these studied plants and their extracts were evaluated through kidneys and liver functions. In the second experiment of this study, the most efficient treatments of the first experiment were studied in animal model of benign prostate hyperplasia (BPH) to evaluate the anti-androgenic effect of the plants under study in an animal model of BPH
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Item type Current library Home library Call number Copy number Status Date due Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.07.04.Ph.D.2015.Ka.B (Browse shelf(Opens below)) Not for loan 01010110067109000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.07.04.Ph.D.2015.Ka.B (Browse shelf(Opens below)) 67109.CD Not for loan 01020110067109000

Thesis (Ph.D.) - Cairo University - Faculty of Agriculture - Department of Agricultural Biochemistry

The present study was designed to evaluate the anti-androgenic effect of some plants in castrated rats (flaxseed, sesame seeds, safflower seeds and soybean seeds) which were analyzed then petroleum ether and ethanol extracts were prepared from these samples. Some phytochemicals such as total phenolic compounds content, fatty acids, hydrocarbons and phytosterols contents were determined in all the studied plants. Also the anti - cancer effect of all the plants powder under investigation were studied against prostate cancer using cell-line technique. In the first experiment of the present study flax, sesame, safflower and soybean seeds were evaluated as anti-androgenic agents in castrated/testosterone rats in form of petroleum ether, ethanol extracts and whole powder. The nutritional safety of these studied plants and their extracts were evaluated through kidneys and liver functions. In the second experiment of this study, the most efficient treatments of the first experiment were studied in animal model of benign prostate hyperplasia (BPH) to evaluate the anti-androgenic effect of the plants under study in an animal model of BPH

Issued also as CD

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