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Detection of cancer stem cells in colorectal cancer : Histopathological and immunohistochemical study / Ahmed Soliman Ahmed Soliman ; Supervised Nour Elhoda Sayed Ismaiel , Walid M. Sharaf , Dina Omar Helmy

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Ahmed Soliman Ahmed Soliman , 2015Description: 156 P. : charts , facsimiles ; 25cmOther title:
  • الكشف عن الخلايا الجذعية السرطانية في سرطان القولون والمستقيم : دراسة هيستوباثولوچية ومناعية [Added title page title]
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  • Issued also as CD
Dissertation note: Thesis (Ph.D.) - Cairo University - Faculty of Medicine- Department of Pathology Summary: Background: Growing evidence supports the notion that the onset of tumorigenesis could occur through cancer stem cells (CSCs). These tumor cells show low proliferative rates, high self-renewal capacity, propensity to differentiate into active proliferating tumor cells & resistance to chemoradiotherapy thus, possibly causing local recurrences & metastasis formation despite treatment. CD44 has been used as a marker to isolate CSCs from colorectal carcinoma (CRC). Objective: To investigate the immunohistochemical expression of cancer stem cells marker (CD44) in CRC and correlate its expression with the clinico-pathological aspects, TNM staging and modified Dukes{u2019} classification
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Item type Current library Home library Call number Copy number Status Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.27.Ph.D.2015.Ah.D (Browse shelf(Opens below)) Not for loan 01010110066910000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.27.Ph.D.2015.Ah.D (Browse shelf(Opens below)) 66910.CD Not for loan 01020110066910000

Thesis (Ph.D.) - Cairo University - Faculty of Medicine- Department of Pathology

Background: Growing evidence supports the notion that the onset of tumorigenesis could occur through cancer stem cells (CSCs). These tumor cells show low proliferative rates, high self-renewal capacity, propensity to differentiate into active proliferating tumor cells & resistance to chemoradiotherapy thus, possibly causing local recurrences & metastasis formation despite treatment. CD44 has been used as a marker to isolate CSCs from colorectal carcinoma (CRC). Objective: To investigate the immunohistochemical expression of cancer stem cells marker (CD44) in CRC and correlate its expression with the clinico-pathological aspects, TNM staging and modified Dukes{u2019} classification

Issued also as CD

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