Dermoscopic and immunohistochemical changes in acquired melanocytic nevi following narrow band ultraviolet-B therapy / Nanees Abdelaleem Abdelmonem Ragab ; Supervised Hesham Abdelmoety Zaher , Safinaz Salah Aldin Sayed , Dalia Ahmed Bassiony
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- التغيرات الدرمسكوبيه و الهستوكيميائيه المناعيه فى الوحمات الصبغيه المكتسبه التابعه للعلاج بالأشعه فوق البنفسجيه- ب ضيقة المدى [Added title page title]
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قاعة الرسائل الجامعية - الدور الاول | المكتبة المركزبة الجديدة - جامعة القاهرة | Cai01.11.10.Ph.D.2015.Na.D (Browse shelf(Opens below)) | Not for loan | 01010110066917000 | ||
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مخـــزن الرســائل الجـــامعية - البدروم | المكتبة المركزبة الجديدة - جامعة القاهرة | Cai01.11.10.Ph.D.2015.Na.D (Browse shelf(Opens below)) | 66917.CD | Not for loan | 01020110066917000 |
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Thesis (Ph.D.) - Cairo University - Faculty of Medicine- Department of Dermatology and Venerology
Background: Acquired Melanocytic Nevi (AMN) have been reported to undergo morphological and dermoscopic changes following exposure to NB-UVB radiation. Objectives: To study the clinical, dermoscopic and immunohistochemical changes in AMN exposed to NB-UVB radiation. Patients and Methods: 40 patients diagnosed with different dermatological conditions were enrolled in the study. Three sessions of suberythemogenic NB-UVB per week were delivered for a total of 30 sessions. For each patient a minimum of 2 nevi were selected. One nevus was surgically removed prior to sessions as control, for the other nevus/nevi dermoscopic images were captured before and after NB-UVB sessions. The images were evaluated for morphological and dermoscopic changes. At the end of the irradiation cycle another nevus was surgically removed. Immunohistochemical assessment of Ki67 (marker of proliferation) and Melan A (marker of melanogenesis) were done for the biopsy specimens
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