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Evaluation of serum paraoxonase I activity in pregnant women with antiphospholipid syndrome during the third trimester and its correlations with fetal and neonatal outcomes / Souliman Milood M. Hamed ; Supervised Gamal Abdelsameea Ibrahim , Dawlat Alsayed Salem , Ahmed Hussein Alsawaf

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Souliman Milood Elmabrouk Hamed , 2015Description: 69 P. : charts ; 25cmOther title:
  • تقييم مستوى نشاط إنزيم الباراوكسينيز1 فى الثلث الأخير من الحمل للحوامل المصابات بمتلازمة أضداد الفوسفوليبيد و علاقته بحالة الجنين و حديثى الولادة [Added title page title]
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Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Gynecology and Obstetrics Summary: From this study we can conclude that a decreased serum paraoxonase I enzyme activity may be responsible at least partially for the derangement of lipid profile that led to the observed changes in fetal parameters such as non - reassuring biophysical profile, elevated umbilical artery resistance index. As well as neonatal abnormalities such as lowered neonatal birth weight and reduced apgar score. Therefore, it can be concluded that assessment of serum paraoxonase I activity, may be applied among the parameters used in monitoring pregnant women with antiphospholipid syndrome. Decreased PON I activity, with increased oxidative stress and reduction of NO, may be involved in the early phases of APS. Further epidemological investigations are required to study activity of serum paraoxonase I during different gestatinal period on large members of normal and patient with antiphospholipid syndrome
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Item type Current library Home library Call number Copy number Status Date due Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.15.M.Sc.2015.So.E (Browse shelf(Opens below)) Not for loan 01010110067136000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.15.M.Sc.2015.So.E (Browse shelf(Opens below)) 67136.CD Not for loan 01020110067136000

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Gynecology and Obstetrics

From this study we can conclude that a decreased serum paraoxonase I enzyme activity may be responsible at least partially for the derangement of lipid profile that led to the observed changes in fetal parameters such as non - reassuring biophysical profile, elevated umbilical artery resistance index. As well as neonatal abnormalities such as lowered neonatal birth weight and reduced apgar score. Therefore, it can be concluded that assessment of serum paraoxonase I activity, may be applied among the parameters used in monitoring pregnant women with antiphospholipid syndrome. Decreased PON I activity, with increased oxidative stress and reduction of NO, may be involved in the early phases of APS. Further epidemological investigations are required to study activity of serum paraoxonase I during different gestatinal period on large members of normal and patient with antiphospholipid syndrome

Issued also as CD

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