Relationship between serum fetuin- a level and insulin resistance index in polycystic ovarian syndrome / Sherif Mohammed Elsirgany ; Supervised Hesham Sayed Badawi , Manal Hamdy Elsaid , Zakaria A.Halim Elkhayat

Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Gynecology and Obstetrics

In this study We found that the fetuin A level in the PCO{u2019}s group was higher than the control group and the difference was statistically significant between two groups (mean ± SD: 521 ± 7.1 vs 505 ± 50.5 ng/ml respectively), where the best cut of value was 515 ng/ml with a sensitivity 100% and specificity 45 % .Also, LH level in the PCO{u2019}s group was higher than control group (6.25± 2.99 vs 4.3±1.7 respectively) and the difference was statistically significant. FSH level in PCO{u2019}s group was lower than control group and the difference was statistically significant (mean ± SD 5.35±1.6 vs 6.5±1.05 respectively). Free testosterone level was higher in the PCO{u2019}s group than control group (mean ± SD 1.7±0.84 vs 1± 0.22 respectively) in which the difference was statistically significant. The fasting level of insulin, fasting blood sugar and HOMA value were higher in PCO{u2019}s group than control group (mean ± SD 26.7± 6.04 vs 11.4±2.8 respectively) (mean± SD 86.2± 15.9 vs 75.5±7.9 respectively) (mean ± SD 5.5± 1.44 vs 2.24±1.13 respectively) where the differences were statistically significant.On the other hand, there was a positive correlation between Fetuin A levels and both Fasting Insulin and HOMA value in the PCO{u2019}s group and the difference were statistically significant. However; there was a positive correlation between each of the following Fetuin A level and LH, free testosterone and Fasting Glucose level in the PCO{u2019}s group and the differences were not statistically significant

Issued also as CD