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Design of optical response magnetic nanocomposites for labeling the mesenchymal stem and cancer cells in liver diseases / Ola Sayed Ahmed Mahmoud ; Supervised Mahmoud H . Abdelkader , Hussein M. Khaled , Mona Bakr Mohamed

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Ola Sayed Ahmed Mahmoud , 2014Description: 165 P. : charts , facsimiles ; 25cmOther title:
  • تصميم متراكبات نانو مغناطيسيه وضوئية لتمييز الخلايا الجذعيه الوسيطه والخلايا السرطانيه فى أمراض الكبد [Added title page title]
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Dissertation note: Thesis (Ph.D.) - Cairo University - National Institute of Laser Enhanced Sciences - Department of laser application in environmental metrology photochemistry and agriculture Summary: A new multifunctional magnato-plasmonic nancomposite (gold magneto Au-Fe3O4 hybrid nanostructure) has been developed to be used as a dual contrast agent for magnetic resonance imaging (MRI) and computed tomography (CT). Gold magneto NPs were synthesized using the chemical co-precipitation method in presence of polyethylamine (PEI) as a capping agent and reducing agent for the gold. The produced nanoparticles have average size around 21 nm in diameter as determined from transmission electron microscopy. The optical and the magnetic properties had been investigated via absorption spectroscopy (UV-VIS) and vibrating sample magnetometer (VSM). The particles show characteristic absorption band due to surface plasmon resonance of the gold shell and a hysteresis loop due to the magnetic core. The crystal structure and chemical composition had been determined via X-Ray diffraction (XRD) and EDX, and the surface properties have been investigated using zeta potential and the FTIR. All the chemical analysis confirmed the formation of the mono-dispersed core{u2013}shell Au- Fe3O4 nanostructure. These nanoparticles were used as labeling material for bone marrow mesenchymal stem cells (BMSCs) in vitro and in vivo.
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Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.24.05.Ph.D.2014.Ol.D (Browse shelf(Opens below)) Not for loan 01010110067266000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.24.05.Ph.D.2014.Ol.D (Browse shelf(Opens below)) 67266.CD Not for loan 01020110067266000

Thesis (Ph.D.) - Cairo University - National Institute of Laser Enhanced Sciences - Department of laser application in environmental metrology photochemistry and agriculture

A new multifunctional magnato-plasmonic nancomposite (gold magneto Au-Fe3O4 hybrid nanostructure) has been developed to be used as a dual contrast agent for magnetic resonance imaging (MRI) and computed tomography (CT). Gold magneto NPs were synthesized using the chemical co-precipitation method in presence of polyethylamine (PEI) as a capping agent and reducing agent for the gold. The produced nanoparticles have average size around 21 nm in diameter as determined from transmission electron microscopy. The optical and the magnetic properties had been investigated via absorption spectroscopy (UV-VIS) and vibrating sample magnetometer (VSM). The particles show characteristic absorption band due to surface plasmon resonance of the gold shell and a hysteresis loop due to the magnetic core. The crystal structure and chemical composition had been determined via X-Ray diffraction (XRD) and EDX, and the surface properties have been investigated using zeta potential and the FTIR. All the chemical analysis confirmed the formation of the mono-dispersed core{u2013}shell Au- Fe3O4 nanostructure. These nanoparticles were used as labeling material for bone marrow mesenchymal stem cells (BMSCs) in vitro and in vivo.

Issued also as CD

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