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Impacts of some genetics variation on coronary artery disease (CAD) in controls and Egyptian patients / Soheir Mahmoud Mahmoud Ibrahim ; Supervised Mahmoud Ahmed Amer , Enas A. Latif Ahmed , Ashraf Huossen Abdelmohsen

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Soheir Mahmoud Mahmoud Ibrahim , 2015Description: 145 P. : charts , facsimiles , photographs ; 25cmOther title:
  • التأثيرات المختلفة لبعض الجينات على مرض الشريان التاجى فى الاصحاء و المرضى المصريين [Added title page title]
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Dissertation note: Thesis (Ph.D.) - Cairo University - Faculty of Science - Department of Zoology Summary: The present study investigated the relationship between the genetic polymorphisms of Angiotensin-converting enzyme (ACE) and Matrix metalloproteinase 3 (MMP-3) genes in Coronary artery disease (CAD).ACE (I/D) and MMP3 (5A/6A) polymorphism was detected using polymerase chain reaction (PCR). The frequencies of D/D, I/D, and I/I genotypes in CAD compared to control group were significantly different (P=<0.05), and the frequencies of 6A/6A, 5A/5A, and 5A/6A genotypes in CAD compared to control group were significantly different (P=<0.05). The D/D polymorphism of the ACE gene and 5A/6A polymorphism of the MMP3 gene is strongly associated with Coronary artery diseases (CAD) in the Egyptian population
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Item type Current library Home library Call number Copy number Status Date due Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.12.21.Ph.D.2015.So.I (Browse shelf(Opens below)) Not for loan 01010110067370000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.12.21.Ph.D.2015.So.I (Browse shelf(Opens below)) 67370.CD Not for loan 01020110067370000

Thesis (Ph.D.) - Cairo University - Faculty of Science - Department of Zoology

The present study investigated the relationship between the genetic polymorphisms of Angiotensin-converting enzyme (ACE) and Matrix metalloproteinase 3 (MMP-3) genes in Coronary artery disease (CAD).ACE (I/D) and MMP3 (5A/6A) polymorphism was detected using polymerase chain reaction (PCR). The frequencies of D/D, I/D, and I/I genotypes in CAD compared to control group were significantly different (P=<0.05), and the frequencies of 6A/6A, 5A/5A, and 5A/6A genotypes in CAD compared to control group were significantly different (P=<0.05). The D/D polymorphism of the ACE gene and 5A/6A polymorphism of the MMP3 gene is strongly associated with Coronary artery diseases (CAD) in the Egyptian population

Issued also as CD

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