Thesis (Ph.D.) - Cairo University - National Cancer Institute - Department of Anesthesia and Pain Relief

This study was carried on sixty patients with pancreatic cancer pain from pain clinic of the National cancer institute, Cairo university. Patients were randomly allocated to two groups. Group one: CT group (30 patients, scheduled for neurolytic celiac plexus block (NCPB) by computed tomography guidance. Group two: C - arm fluoroscopy group (30 patients, scheduled for neurolytic celiac plexus block (NCPB) by C - arm fluoroscopic guidance (control group). Visual analogue scale, reduction in daily opioid consumption were recorded before the block, 2 hr, 2 days, 2 weeks and 3 weeks post block, time of the procedure estimated and encountered side effects were recorded in each group. All patients were subjected to the following: Full history taking. Through clinical examination. CPB by one of the above techniques. Pain assessment (VAS). Daily morphine consumption. Time of the block. The data were recorded and statistically analyzed, we found that the mean values of VAS were decreased in the two groups, and there was no significant difference between CT and C - arm fluoroscopy groups. In addition, daily morphine consumption was significantly reduced after neurolysis but without significant difference between both groups

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