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The possible effect of certain natural products in chemically induced ulcerative colitis in rats / Yomna Tantawi Abdou Ahmed ; Supervised Sanaa A. Kenawy , Hala Fahmy Zaki

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Yomna Tantawi Abdou Ahmed , 2015Description: 125 P. : charts , photographs ; 25cmOther title:
  • التأثير المحتمل لبعض المنتجات الطبيعية في إلتھاب القولون التقرحي المحدث كميائياً في الجرذان [Added title page title]
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  • Issued also as CD
Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmacology and Toxicology Summary: The present study was constructed in order to investigate the colonic response to iodoacetamide (IA) injection as a model for induction of UC in rats. The aim was extended to study the possible protective effects of GSE, NG and EA in comparison with sulfasalazine, as a standard anti-inflammatory drug, on IA-induced UC in rats. To achieve the goals of the present study, inflammatory markers such as colonic contents of prostaglandins E and total nitrate/nitrite as well as inducible 2 nitric oxide synthase were evaluated. Moreover, pro-inflammatory cytokines such as colonic tumor necrosis factor-alpha and interlukin -8 contents as well as colon myeloperoxidase activity as markers for neutrophils infiltration in response to IA were also estimated
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Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.08.09.M.Sc.2015.Yo.P (Browse shelf(Opens below)) Not for loan 01010110067389000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.08.09.M.Sc.2015.Yo.P (Browse shelf(Opens below)) 67389.CD Not for loan 01020110067389000

Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmacology and Toxicology

The present study was constructed in order to investigate the colonic response to iodoacetamide (IA) injection as a model for induction of UC in rats. The aim was extended to study the possible protective effects of GSE, NG and EA in comparison with sulfasalazine, as a standard anti-inflammatory drug, on IA-induced UC in rats. To achieve the goals of the present study, inflammatory markers such as colonic contents of prostaglandins E and total nitrate/nitrite as well as inducible 2 nitric oxide synthase were evaluated. Moreover, pro-inflammatory cytokines such as colonic tumor necrosis factor-alpha and interlukin -8 contents as well as colon myeloperoxidase activity as markers for neutrophils infiltration in response to IA were also estimated

Issued also as CD

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