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Some substances which may act like beta pancreatic cells with some trials on educational technology / Sherif Hamed Ibrahim Elmosalamy ; Supervised Atef Aziz Salib , Helmy Abdelhamid Salem , Mohamed Zohdy

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Sherif Hamed Ibrahim Elmosalamy , 2015Description: 182 P. : charts , photographs ; 25cmOther title:
  • بعض المواد التى قد تقوم بعمل خلايا بيتا البنكرياسية مع استخدام بعض محاولات تكنولوجيا التعليم [Added title page title]
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Dissertation note: Thesis (Ph.D.) - Cairo University - Faculty of Veterinary Medicine - Department of Animal Physiology Summary: The present study was performed to study the physiological effects of alpha lipoic acid, vanadyl acetylacetonate and nigella sativa in diabetic rats. A total of 110 mature male sprague - dawley rats were randomly allocated into 5 groups: control, untreated diabetic, alpha lipoic acid, vanadyl acetylacetonate and nigella sativa. After 2,4 and 6 weeks from onset of diabetes, serum and plasma samples were obtained for estimation of fasting blood glucose, lipid profile, liver and kidney functions. Histopathological samples were taken from liver, kidney and pancreas. Administration of alpha lipoic acid, vanadyl acetylacetonate and nigella sativa to diabetic rats resulted in a significant decrease (P < 0.05) in blood glucose and lipid profile and improvement in liver and kidney functions when compared to untreated diabetic rats. The histopathological findings in liver, kidney and pancreas of treated groups showed improvement when compared with those of diabetic group. The results of this study indicate that the alpha lipoic acid, vanadyl acetylacetonate and nigella sativa possess hypoglycemic, hypolipidemic, improvement effects on kidney and liver functions and protective effects on beta cells of pancreas in streptozotocin induced diabetic rats
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Item type Current library Home library Call number Copy number Status Date due Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.10.16.Ph.D.2015.Sh.S (Browse shelf(Opens below)) Not for loan 01010110067613000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.10.16.Ph.D.2015.Sh.S (Browse shelf(Opens below)) 67613.CD Not for loan 01020110067613000

Thesis (Ph.D.) - Cairo University - Faculty of Veterinary Medicine - Department of Animal Physiology

The present study was performed to study the physiological effects of alpha lipoic acid, vanadyl acetylacetonate and nigella sativa in diabetic rats. A total of 110 mature male sprague - dawley rats were randomly allocated into 5 groups: control, untreated diabetic, alpha lipoic acid, vanadyl acetylacetonate and nigella sativa. After 2,4 and 6 weeks from onset of diabetes, serum and plasma samples were obtained for estimation of fasting blood glucose, lipid profile, liver and kidney functions. Histopathological samples were taken from liver, kidney and pancreas. Administration of alpha lipoic acid, vanadyl acetylacetonate and nigella sativa to diabetic rats resulted in a significant decrease (P < 0.05) in blood glucose and lipid profile and improvement in liver and kidney functions when compared to untreated diabetic rats. The histopathological findings in liver, kidney and pancreas of treated groups showed improvement when compared with those of diabetic group. The results of this study indicate that the alpha lipoic acid, vanadyl acetylacetonate and nigella sativa possess hypoglycemic, hypolipidemic, improvement effects on kidney and liver functions and protective effects on beta cells of pancreas in streptozotocin induced diabetic rats

Issued also as CD

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