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The possible teratogenic effect of fluconazol on craniofacial development in albino rat / Abdalsattar Abdalsattar Ibraheim ; Supervised Nabila Yousef Abdalhalim , Ehab Abdelaziz Ahmed , Gamal Hosney Mohamed

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : AbdAlsattar AbdAlsattar Ibraheim , 2015Description: 84 P. : charts , facsimiles ; 25cmOther title:
  • التشوهات الخلقية المحتملة فى الوجه و الجمجمة الناتجة عن استخدام الفلوكونازول فى الفأر الأبيض [Added title page title]
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Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Anatomy Summary: fluconazole has been considered one of the most effective antifungal drugs used in oral, systemic and vaginal candidiasis, and has also been used in agriculture insecticides. The present Study was done to determine the teratogenic effect of fluconazole on craniofacial development in albino rat, and to evaluate this effect in relation to different doses.In this work, 40 pregnant rats of norvigicus strain were used and devided into 4 groups. The 1st group "A" consisted of 10 pregnant rats and used as a control group that received nothing. The 2nd group "B" consisted of 10 pregnant rats and used as sham control group, this group received normal saline by intraperitoneal injection from day 8 to day 13 of pregnancy. The 3rd group"C1" consisted of 10 pregnant rats that received 40 mg/kg/day of fluconazole by intraperitoneal injection from day 8 to day 13 of pregnancy. The 4th group "C2" consisted of 10 pregnant rats that received 80 mg/kg/day fluconazole by intraperitoneal injection from day 8 to day 13 of pregnancy
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Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.02.M.Sc.2015.Ab.P (Browse shelf(Opens below)) Not for loan 01010110067407000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.02.M.Sc.2015.Ab.P (Browse shelf(Opens below)) 67407.CD Not for loan 01020110067407000

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Anatomy

fluconazole has been considered one of the most effective antifungal drugs used in oral, systemic and vaginal candidiasis, and has also been used in agriculture insecticides. The present Study was done to determine the teratogenic effect of fluconazole on craniofacial development in albino rat, and to evaluate this effect in relation to different doses.In this work, 40 pregnant rats of norvigicus strain were used and devided into 4 groups. The 1st group "A" consisted of 10 pregnant rats and used as a control group that received nothing. The 2nd group "B" consisted of 10 pregnant rats and used as sham control group, this group received normal saline by intraperitoneal injection from day 8 to day 13 of pregnancy. The 3rd group"C1" consisted of 10 pregnant rats that received 40 mg/kg/day of fluconazole by intraperitoneal injection from day 8 to day 13 of pregnancy. The 4th group "C2" consisted of 10 pregnant rats that received 80 mg/kg/day fluconazole by intraperitoneal injection from day 8 to day 13 of pregnancy

Issued also as CD

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