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Paracetamol versus indomethacin and ibuprofen administration in management of patent ductus arteriosus in premature infants / Nahed Abdelmordy Mashhout ; Supervised Ayman Abdelrahman Elbadawy , Samar Mohammed Elmamoon , Wael Ahmed Attia

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Nahed Abdelmordy Mashhout , 2015Description: 102 P. : charts , facsimiles ; 25cmOther title:
  • مقارنة عقار الباراسيتامول بعقارى الاندوميثاسين و الابيبروفين فى علاج الوصلة الشريانية المفتوحة فى الاطفال المبتسرين [Added title page title]
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Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics Summary: This study was to determine the efficacy and safety of intravenous paracetamol in closure of hemodynamically significant PDA in premature neonates in comparison to ibuprofen and indomethacin. The study included 40 premature infants {u2264} 36 weeks gestational age admitted to Kasr Alainy hospital, NICU units, Cairo university between October 2013 and August 2014 whom had clinically significant PDA. 20 cases received intravenous paracetamol. 17 had their PDA closed after 1st course with closure rate of 85%, 3 cases received 2nd course, 2 of total 3 infants had their PDA closed with closure rate of 10%.10 cases received oral ibuprofen 8 had their PDA closed after 1st course with closure rate of 80%, 2 cases received 2nd course, one case had PDA closure with closure rate 10% and 10 cases received intravenous indomethacin 7 had their PDA closed after 1st course with closure rate 70%. 3 cases received 2nd course, 2 cases had PDA closure with closure rate 20%. Monitoring of hepatic functions pre and post treatment showed no significant adverse effects related to treatment
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Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.28.M.Sc.2015.Na.P (Browse shelf(Opens below)) Not for loan 01010110067862000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.28.M.Sc.2015.Na.P (Browse shelf(Opens below)) 67862.CD Not for loan 01020110067862000

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics

This study was to determine the efficacy and safety of intravenous paracetamol in closure of hemodynamically significant PDA in premature neonates in comparison to ibuprofen and indomethacin. The study included 40 premature infants {u2264} 36 weeks gestational age admitted to Kasr Alainy hospital, NICU units, Cairo university between October 2013 and August 2014 whom had clinically significant PDA. 20 cases received intravenous paracetamol. 17 had their PDA closed after 1st course with closure rate of 85%, 3 cases received 2nd course, 2 of total 3 infants had their PDA closed with closure rate of 10%.10 cases received oral ibuprofen 8 had their PDA closed after 1st course with closure rate of 80%, 2 cases received 2nd course, one case had PDA closure with closure rate 10% and 10 cases received intravenous indomethacin 7 had their PDA closed after 1st course with closure rate 70%. 3 cases received 2nd course, 2 cases had PDA closure with closure rate 20%. Monitoring of hepatic functions pre and post treatment showed no significant adverse effects related to treatment

Issued also as CD

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