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Role of vascular endothelial growth factor (VEGF) in the prognosis and management of hepatocellular carcinoma HCC / Mohamed Esmat Mahmoud ; Supervised Heba Mohamed Alzawahry , Yasser Ahmed Sallam , Heba Mohamed Shaaban

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Mohamed Esmat Mahmoud , 2015Description: 104 P. ; 25cmOther title:
  • دور معامل التخثر الوريدى فى متابعة تطورات و علاج أورام الكبد [Added title page title]
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Dissertation note: Thesis (M.Sc.) - Cairo University - National Cancer Institute - Department of Oncology - Medical Summary: Role of vascular endothelial growth factor in prognosis and management of hepatocellular carcinoma. Association of VEGF overexpression with poor outcomes provides a rationale for anti - angiogenics use in the treatment of cancer. VEGF has become a leading therapeutic target for the treatment of cancer. Potentially therapeutic strategies to inhibit VEGF pathway include monoclonal antibodies directed against VEGF and tyrosine kinase inhibitors (TKIs). In conclusion, results suggest that plasma IGF - 1 may serve as a new tool for assessing liver reserve in patients with HCC and that baseline plasma assessment of both IGF - 1 and VEGF significantly improves prediction of OS and prognostic stratification of patients with HCC according to BCLC staging
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Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.19.04.M.Sc.2015.Mo.R (Browse shelf(Opens below)) Not for loan 01010110067880000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.19.04.M.Sc.2015.Mo.R (Browse shelf(Opens below)) 67880.CD Not for loan 01020110067880000

Thesis (M.Sc.) - Cairo University - National Cancer Institute - Department of Oncology - Medical

Role of vascular endothelial growth factor in prognosis and management of hepatocellular carcinoma. Association of VEGF overexpression with poor outcomes provides a rationale for anti - angiogenics use in the treatment of cancer. VEGF has become a leading therapeutic target for the treatment of cancer. Potentially therapeutic strategies to inhibit VEGF pathway include monoclonal antibodies directed against VEGF and tyrosine kinase inhibitors (TKIs). In conclusion, results suggest that plasma IGF - 1 may serve as a new tool for assessing liver reserve in patients with HCC and that baseline plasma assessment of both IGF - 1 and VEGF significantly improves prediction of OS and prognostic stratification of patients with HCC according to BCLC staging

Issued also as CD

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