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A study of anesthetic agents induced genotoxicity : Kasr Elaini Hospitals{u2019} experience / Azza Abdelhamied Abdelatti Rady ; Supervised Dina Ali Shokry , Hala Saied Zaghloul , Abeer Ahmed Zayed

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Azza Abdelhamied Abdelatti Rady , 2015Description: 105 P. : charts ; 25cmOther title:
  • دراسة التسمم الجيني الناتج عن عقاقير التخدير : تجربة مستشفيات قصر العيني [Added title page title]
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Dissertation note: Thesis (Ph.D.) - Cairo University - Faculty of Medicine- Department of Forensic Med-Toxicology Summary: Exposure to waste anesthetic gases carries significant health hazards; genotoxicity is an identified risk among others. This study was conducted to evaluate the possible genotoxic effects of waste anesthetic gases on exposed medical personnel working in Kasr Al Aini hospitals. Sister chromatid exchanges (SCE) and micronucleus tests (MN) were performed on 31 exposed and 32 non exposed subjects. Both SCE and MN showed significant difference between the two groups. SCE was correlated to MN in the exposed group. SCE and MN significantly increased with age and duration of work. However no effect of smoking or sex was observed. Comet assay was performed on 32 operation room (OR) personnel and 35 non exposed. The study revealed significantly increased comet parameters (mean comet tail length and moment) in peripheral blood lymphocytes of OR personnel in comparison with control individuals
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Item type Current library Home library Call number Copy number Status Date due Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.13.Ph.D.2015.Az.S (Browse shelf(Opens below)) Not for loan 01010110067891000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.13.Ph.D.2015.Az.S (Browse shelf(Opens below)) 67891.CD Not for loan 01020110067891000

Thesis (Ph.D.) - Cairo University - Faculty of Medicine- Department of Forensic Med-Toxicology

Exposure to waste anesthetic gases carries significant health hazards; genotoxicity is an identified risk among others. This study was conducted to evaluate the possible genotoxic effects of waste anesthetic gases on exposed medical personnel working in Kasr Al Aini hospitals. Sister chromatid exchanges (SCE) and micronucleus tests (MN) were performed on 31 exposed and 32 non exposed subjects. Both SCE and MN showed significant difference between the two groups. SCE was correlated to MN in the exposed group. SCE and MN significantly increased with age and duration of work. However no effect of smoking or sex was observed. Comet assay was performed on 32 operation room (OR) personnel and 35 non exposed. The study revealed significantly increased comet parameters (mean comet tail length and moment) in peripheral blood lymphocytes of OR personnel in comparison with control individuals

Issued also as CD

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