Effectiveness of oral versus vaginal misoprostol before office hysteroscopy in infertile patients / Kareem Ahmed Mohammed Elbegawy ; Supervised Mohamad Mohamad Ismaeil Elbokl , Nadine Alaa Sherif , Yomna Ali Bayoumi

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Obstetrics and Gynecology

Primary infertility can be defined as the failure to achieve a pregnancy within one year of regular unprotected intercourse; secondary infertility means failure to conceive after 2 years of continuous marital life without use of contraception after the previous pregnancy. It is widely accepted that a complete infertility workup should include an evaluation of the uterine cavity. The role of hysteroscopy in infertility investigation is to detect possible intrauterine changes that could interfere with implantation or growth or both of the conceptus, with the invention of miniature hysteroscope, it is possible to perform hysteroscopy in an office setting (Outpatient hysteroscopy; OH), for diagnostic and certain therapeutic intervention. It is currently acknowledged as the {u2018}gold standard{u2019} investigation of the intrauterine abnormalities. Cervical priming prior to diagnostic hysteroscopy softens the cervix and lessens the force needed for dilation, thereby potentially reducing the probability of procedural complication such as uterine perforation, cervical laceration, failure to dilate, and creation of a false track that can occur during cervical entry. Cervical ripening is clinically diagnosed by softening, effacement, and dilatation of the uterine cervix

Issued also as CD