header
Local cover image
Local cover image
Image from OpenLibrary

Efficacy and safety of milrinone versus sildenafil in the management of moderate to severe peristent pulmonary hypertention in neonates / Mohamed Salah Thabet ; Supervised Zahraa Mohamed Ezz Eldein , Hanan Zekry Khaled , Tamer Abdelhamed Dihome

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Mohamed Salah Thabet , 2015Description: 123 P. : facsimiles ; 25cmOther title:
  • دراسة مدى كفاءة و مدى امان عقار الميلرينون وعقارالسيلدنافيل في علاج إرتفاع ضغط الشريان الرئوي في الاطفال حديثي الولاده [Added title page title]
Subject(s): Online resources: Available additional physical forms:
  • Issued also as CD
Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics Summary: Background: Pulmonary hypertension in newborn (PPHN) is a critical problem facing neonatologists. Aim of the work: To determine the impact of management strategies on the outcome of PPHN. Patients and methods: Prospective descriptive study. 40 neonates with the diagnosis of PPHN who were admitted in NICUs in multi-centers from June 2014 to December 2014. Neonates divided into 2 equal groups one is treated by intravenous milrinone infusion and the other is treated by nasogastric sildenafil, it includes 33 males, 7 females; their mean gestational age was ±36.5weeks and the mean weight was 2.9 ± 0.5Kg. Results: Male neonates had higher incidence of PPHN 82.5% compared to females 17.5% .Neonates recived intravenous milrinone infusion shows statistical significant improvement than those recived nasogastric sildenafil in oxygenation index (OI)values 24 hrs after treatment(p{u2264}0.010), 48 hrs later (P{u2264} 0.001). Successful treatment was defined as drop of systolic pulmonary artery pressure (SPAP) below {u2264}40mmHg. There was statistical significant drop of SPAP after application ofmilrinone than sildenafil (P{u2264}0.040). The mortality rate was 10/40 neonates (25%)
Tags from this library: No tags from this library for this title. Log in to add tags.
Star ratings
    Average rating: 0.0 (0 votes)
Holdings
Item type Current library Home library Call number Copy number Status Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.28.M.Sc.2015.Mo.E (Browse shelf(Opens below)) Not for loan 01010110067905000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.28.M.Sc.2015.Mo.E (Browse shelf(Opens below)) 67905.CD Not for loan 01020110067905000

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics

Background: Pulmonary hypertension in newborn (PPHN) is a critical problem facing neonatologists. Aim of the work: To determine the impact of management strategies on the outcome of PPHN. Patients and methods: Prospective descriptive study. 40 neonates with the diagnosis of PPHN who were admitted in NICUs in multi-centers from June 2014 to December 2014. Neonates divided into 2 equal groups one is treated by intravenous milrinone infusion and the other is treated by nasogastric sildenafil, it includes 33 males, 7 females; their mean gestational age was ±36.5weeks and the mean weight was 2.9 ± 0.5Kg. Results: Male neonates had higher incidence of PPHN 82.5% compared to females 17.5% .Neonates recived intravenous milrinone infusion shows statistical significant improvement than those recived nasogastric sildenafil in oxygenation index (OI)values 24 hrs after treatment(p{u2264}0.010), 48 hrs later (P{u2264} 0.001). Successful treatment was defined as drop of systolic pulmonary artery pressure (SPAP) below {u2264}40mmHg. There was statistical significant drop of SPAP after application ofmilrinone than sildenafil (P{u2264}0.040). The mortality rate was 10/40 neonates (25%)

Issued also as CD

There are no comments on this title.

to post a comment.

Click on an image to view it in the image viewer

Local cover image