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Immunohistochemical expression of P27kip1 in oral squamous cell carcinoma / Pasant Tarek Mohammed Thakeb ; Supervised Heba Farg , Dina Soliman Khater

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Pasant Tarek Mohammed Thakeb , 2014Description: 101P. : facsimiles ; 25cmOther title:
  • الانتشار الهيستوكيميائي المناعي لب ك ي ب١ ٢٧ في سرطان الخلايا الحرفشية الفمي [Added title page title]
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Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Oral and Dental Medicine- Department of Oral Pathology Summary: p27Kip1 is a member of a family of cyclin dependent kinase (CDK) inhibitors that bind to cyclin/CDK complexes and arrest cell division. There is considerable evidence that p27Kip1 plays an important role in multiple fundamental cellular processes, including cell proliferation, cell differentiation, and apoptosis. This study was performed to investigate the immunohistochemical expression of p27kip1in OSCC and to correlate this expression with different grades in order to evaluate its role in progression. Five , normal control cases where selected from paraffin blocks of mesenchymal where the normal surface epithelium was considered the normal control. Thirty cases of paraffin blocks were investigated in the study were 14 specimens well differentiated, 7 specimens moderately differentiated and 9 specimens were poorly differentiated OSCC
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Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.09.04.M.Sc.2014.Pa.I (Browse shelf(Opens below)) Not for loan 01010110067933000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.09.04.M.Sc.2014.Pa.I (Browse shelf(Opens below)) 67933.CD Not for loan 01020110067933000

Thesis (M.Sc.) - Cairo University - Faculty of Oral and Dental Medicine- Department of Oral Pathology

p27Kip1 is a member of a family of cyclin dependent kinase (CDK) inhibitors that bind to cyclin/CDK complexes and arrest cell division. There is considerable evidence that p27Kip1 plays an important role in multiple fundamental cellular processes, including cell proliferation, cell differentiation, and apoptosis. This study was performed to investigate the immunohistochemical expression of p27kip1in OSCC and to correlate this expression with different grades in order to evaluate its role in progression. Five , normal control cases where selected from paraffin blocks of mesenchymal where the normal surface epithelium was considered the normal control. Thirty cases of paraffin blocks were investigated in the study were 14 specimens well differentiated, 7 specimens moderately differentiated and 9 specimens were poorly differentiated OSCC

Issued also as CD

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