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The evaluation of green tea extract as a therapeutic agent against electromagnetic radiation-induced oxidative stress in some brain regions of the adult rat / Noha Mohamed Abdelfattah Sobhy ; Supervised Nawal Abdelhay Ahmed , Nasr Mahmoud Radwan , Heba Salah Eldin Aboulezz

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Noha Mohamed Abdelfattah Sobhy , 2015Description: 184 P. : charts ; 25cmOther title:
  • تق{u٠٦أأ}{u٠٦أأ}م خلاصة الشاى الأخضر كعامل علاجى ضد الاجھاد التأكسدى الناتج عن الاشعاع الكھرومغناط{u٠٦أأ}سى فى بعض مناطق دماغ الجرذ الأب{u٠٦أأ}ض البالغ [Added title page title]
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Dissertation note: Thesis (Ph.D.) - Cairo University - Faculty of Science - Department of Zoology Summary: The aim of the present study is to investigate the effect of EMR (frequency 900 MHz modulated at 217 Hz, power density 0.02 mW/cm2 , SAR 1.245 W/kg) on malondialdehyde, nitric oxide, catalase, reduced glutathione, glutathione reductase and superoxide dismutase in the hippocampus, cortex, striatum and hypothalamus of adult rats. This study also extends to evaluate the therapeutic effect of green tea extract (150 mg/kg) on the previous mentioned parameters in animals exposed to EMR after exposure and during EMR exposure. Disturbances in oxidant and antioxidant parameters were recorded in the selected brain areas after EMR exposure. These disturbances suggest that a state of oxidative stress may occur in the brain after EMR, being more prominent in the hippocampus and striatum. Co-administration of green tea extract at the beginning of EMR exposure for 2 and 3 months in the studied brain areas has a more beneficial effect against EMR-induced oxidative stress than oral administration of green tea extract after exposure was started
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Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.12.21.Ph.D.2015.No.E (Browse shelf(Opens below)) Not for loan 01010110068083000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.12.21.Ph.D.2015.No.E (Browse shelf(Opens below)) 68083.CD Not for loan 01020110068083000

Thesis (Ph.D.) - Cairo University - Faculty of Science - Department of Zoology

The aim of the present study is to investigate the effect of EMR (frequency 900 MHz modulated at 217 Hz, power density 0.02 mW/cm2 , SAR 1.245 W/kg) on malondialdehyde, nitric oxide, catalase, reduced glutathione, glutathione reductase and superoxide dismutase in the hippocampus, cortex, striatum and hypothalamus of adult rats. This study also extends to evaluate the therapeutic effect of green tea extract (150 mg/kg) on the previous mentioned parameters in animals exposed to EMR after exposure and during EMR exposure. Disturbances in oxidant and antioxidant parameters were recorded in the selected brain areas after EMR exposure. These disturbances suggest that a state of oxidative stress may occur in the brain after EMR, being more prominent in the hippocampus and striatum. Co-administration of green tea extract at the beginning of EMR exposure for 2 and 3 months in the studied brain areas has a more beneficial effect against EMR-induced oxidative stress than oral administration of green tea extract after exposure was started

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