header
Image from OpenLibrary

Evaluation of some possible biomarkers for bladder cancer / Mohammad Jamal 2Alhaj Abdul Aziz3 Saadeh ; Supervised Sanaa O. Abdallah , Abdelfattah M. Attallah

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Mohammad Jamal 2Alhaj Abdul Aziz3 Saadeh , 2015Description: 141 P. : charts , facsimiles ; 25cmOther title:
  • تقييم بعض الدلالات البيولوجية المحتملة لسرطان المثانة [Added title page title]
Subject(s): Available additional physical forms:
  • Issued also as CD
Dissertation note: Thesis (Ph.D.) - Cairo University - Faculty of Science - Department of Biochemistry Summary: Bladder cancer (BC) is one of the most common tumors of genitourinary tract. Therefore, the identification of Nuclear Matrix protein (NMP-52) is a critical step toward accurate diagnosis of BC. Western blot using monospecific anti-NMP-52 antibody were used to identify NMP-52 marker in urine sample from patients with BC, then the NMP-52 was purified. Urine samples were obtained from 40 healthy individuals, 54 cystitis patients, and 62 patients with bladder cancer. The NMP-52 levels in the urine samples were measured using ELISA methods. The mean urinary NMP-52 level in healthy individuals, cystitis and patients with bladder cancer was 0.72, 3.82, and 17.85 æg/ml, respectively. The AUC of NMP was 0.89. The sensitivity and specificity were 94% and 82% at cutoff value equal 2.2 æg/ml. Our data demonstrated that NMP- 52 is a good diagnostic tool for screening BC owing to its high sensitivity and specificity
Tags from this library: No tags from this library for this title. Log in to add tags.
Star ratings
    Average rating: 0.0 (0 votes)
Holdings
Item type Current library Home library Call number Copy number Status Date due Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.12.02.Ph.D.2015.Mo.E (Browse shelf(Opens below)) Not for loan 01010110068175000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.12.02.Ph.D.2015.Mo.E (Browse shelf(Opens below)) 68175.CD Not for loan 01020110068175000

Thesis (Ph.D.) - Cairo University - Faculty of Science - Department of Biochemistry

Bladder cancer (BC) is one of the most common tumors of genitourinary tract. Therefore, the identification of Nuclear Matrix protein (NMP-52) is a critical step toward accurate diagnosis of BC. Western blot using monospecific anti-NMP-52 antibody were used to identify NMP-52 marker in urine sample from patients with BC, then the NMP-52 was purified. Urine samples were obtained from 40 healthy individuals, 54 cystitis patients, and 62 patients with bladder cancer. The NMP-52 levels in the urine samples were measured using ELISA methods. The mean urinary NMP-52 level in healthy individuals, cystitis and patients with bladder cancer was 0.72, 3.82, and 17.85 æg/ml, respectively. The AUC of NMP was 0.89. The sensitivity and specificity were 94% and 82% at cutoff value equal 2.2 æg/ml. Our data demonstrated that NMP- 52 is a good diagnostic tool for screening BC owing to its high sensitivity and specificity

Issued also as CD

There are no comments on this title.

to post a comment.