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Mean platelet volume as a useful indicator of systemic inflammation in cirrhotic patients with spontaneous bacterial peritonitis / Gehan Said Sdeek Alkhshin ; Supervised Emad Mohammed Elmotasem , Mervat Essam Eldin Behiry , Dina Mohammed Hassan

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Gehan Said Sdeek Alkhshin , 2015Description: 203 P. : facsimiles ; 25cmOther title:
  • متوسط حجم الصفائح الدموية كدليل قيّم على حدوث التهاب فى مرضى التليف الكبدى المصاحب بإلتهاب الغشاء البريتونى [Added title page title]
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Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Internal Medicine Summary: Spontaneous bacterial peritonitis (SBP) is the most common infection with a high morbidity and mortality in cirrhotic patients with ascites. Mean platelet volume (MPV) is an indicator of active platelets with more proinflammatory actions. The present study was aiming to prove that increased MPV is an indicator of inflammatory processes in SBP. It was conducted on 50 patients with liver cirrhosis and ascites and 30 healthy subjects as controls. Routine laboratory investigations including: CBC with MPV estimation, ESR, CRP, ascitic fluid examination for cirrhotic patients and abdominal ultrasound done for all patients and compared to controls. MPV was significantly higher in patient than controls (11.0 ± 1.2 and 9.9 ± 0.9) respectively with (P. value < 0.001). At a cutoff value {u2265} 10.8fl, MPV had 82.5% sensitivity and 100% specificity for detecting SBP. MPV increases in cirrhotic patients with ascitic fluid infection, indicating occurrence of systemic inflammatory response
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Item type Current library Home library Call number Copy number Status Date due Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.18.M.Sc.2015.Ge.M (Browse shelf(Opens below)) Not for loan 01010110068345000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.18.M.Sc.2015.Ge.M (Browse shelf(Opens below)) 68345.CD Not for loan 01020110068345000

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Internal Medicine

Spontaneous bacterial peritonitis (SBP) is the most common infection with a high morbidity and mortality in cirrhotic patients with ascites. Mean platelet volume (MPV) is an indicator of active platelets with more proinflammatory actions. The present study was aiming to prove that increased MPV is an indicator of inflammatory processes in SBP. It was conducted on 50 patients with liver cirrhosis and ascites and 30 healthy subjects as controls. Routine laboratory investigations including: CBC with MPV estimation, ESR, CRP, ascitic fluid examination for cirrhotic patients and abdominal ultrasound done for all patients and compared to controls. MPV was significantly higher in patient than controls (11.0 ± 1.2 and 9.9 ± 0.9) respectively with (P. value < 0.001). At a cutoff value {u2265} 10.8fl, MPV had 82.5% sensitivity and 100% specificity for detecting SBP. MPV increases in cirrhotic patients with ascitic fluid infection, indicating occurrence of systemic inflammatory response

Issued also as CD

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