Obesity-related colorectal carcinoma through insulin resistance, insulin growth factor-1 (IGF-1) And IGF binding protein-3 (IGFBP-3) and their genetic polymorphism / Mohamed Yousef Salah ; Supervised Ayman Yousry Abdelrahim , Mohammad Salah Abdelbary , Sherif Hamdy
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- العلاقة ما بين السمنة وأورام القولون السرطانية من خلال مقاومة الأنسولين و معامل نمو الأنسولين رقم {u٠٦ئ١} والبروتين الرابط رقم {u٠٦ئ٣} و الاختلال الجيني لهم [Added title page title]
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Item type | Current library | Home library | Call number | Copy number | Status | Barcode | |
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قاعة الرسائل الجامعية - الدور الاول | المكتبة المركزبة الجديدة - جامعة القاهرة | Cai01.11.33.Ph.D.2015.Mo.O (Browse shelf(Opens below)) | Not for loan | 01010110068530000 | ||
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مخـــزن الرســائل الجـــامعية - البدروم | المكتبة المركزبة الجديدة - جامعة القاهرة | Cai01.11.33.Ph.D.2015.Mo.O (Browse shelf(Opens below)) | 68530.CD | Not for loan | 01020110068530000 |
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Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Tropical Medicine
In Egypt, CRC represents about 4% of total cancers in both sexes. Variation in environmental risk factors particularly the higher content of dietary fibers, more physical activity and lower obesity rates can explain for the different incidence rates between Egypt and the western countries . The increased IGF-I bioavailability may, over time, increase the risk of colorectal cancer. This new evidence for biologic interactions among insulin, IGF-I, and IGFBPs in the context of colorectal carcinogenesis provides a potential mechanism through which diet and associated factors may increase the risk of this cancer
Issued also as CD
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