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Prognostic value of the biomarker copeptin in critically ill patients with sepsis / Mohammed Gomaa Hammad ; Supervised Elham Mohammed Sobhy , Mervat Mohammed Naguib , Laila Ahmed Rashed

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Mohammed Gomaa Hammad , 2015Description: 98 P. : charts ; 25cmOther title:
  • القيمه الانذاريه للكوببتين كعلامه حيويه فى المرضى ذوى الحالات الحرجه و الانتان [Added title page title]
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  • Issued also as CD
Dissertation note: Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Internal Medicine Summary: Background: Sepsis is a major challenge in ICU and it is associated with high mortality. Early diagnosis and quantification of its severity will allow appropriate management and may help in improving outcome. Many researchers have focused on factors that predict mortality in sepsis and many biomarkers have been postulated as predictors of outcomes.Copeptin, the C-terminal fragment of arginine vasopressin (AVP), has been suggested as stress hormone and a stable surrogate marker for the unstable AVP. Objective: The work will study the relation between Copeptin and the outcome in patients with sepsis in terms of mortality as primary end point and multiple organ failure as secondary outcome . Results: copeptin can be a biomarker for severity and outcome in patients with sepsis and sensitive predictor of mortality and MOF development. Correlation of copeptin with creatinin concentration may identify patients with sepsis who develop renal impairment and Copeptin can diagnose sepsis complicating cardiac patients and help improve their outcome. Conclusion: copeptin can be a biomarker for severity and outcome in patients with sepsis and sensitive predictor of mortality and MOF development
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Item type Current library Home library Call number Copy number Status Date due Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.18.Ph.D.2015.Mo.P (Browse shelf(Opens below)) Not for loan 01010110068556000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.18.Ph.D.2015.Mo.P (Browse shelf(Opens below)) 68556.CD Not for loan 01020110068556000

Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Internal Medicine

Background: Sepsis is a major challenge in ICU and it is associated with high mortality. Early diagnosis and quantification of its severity will allow appropriate management and may help in improving outcome. Many researchers have focused on factors that predict mortality in sepsis and many biomarkers have been postulated as predictors of outcomes.Copeptin, the C-terminal fragment of arginine vasopressin (AVP), has been suggested as stress hormone and a stable surrogate marker for the unstable AVP. Objective: The work will study the relation between Copeptin and the outcome in patients with sepsis in terms of mortality as primary end point and multiple organ failure as secondary outcome . Results: copeptin can be a biomarker for severity and outcome in patients with sepsis and sensitive predictor of mortality and MOF development. Correlation of copeptin with creatinin concentration may identify patients with sepsis who develop renal impairment and Copeptin can diagnose sepsis complicating cardiac patients and help improve their outcome. Conclusion: copeptin can be a biomarker for severity and outcome in patients with sepsis and sensitive predictor of mortality and MOF development

Issued also as CD

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