header
Local cover image
Local cover image
Image from OpenLibrary

Health related quality of life in rheumatoid arthritis patients : Correlation with disease activity, disability index and radiological damage / Ayman Eid Girgis ; Supervised Ola Mohammed Ragab , Hania Salah Zayed , Enas Abolkheir Abdelaleem

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Ayman Eid Girgis , 2015Description: 198 P. : charts ; 25cmOther title:
  • نوعية الحياة المتعلقة بالصحة لمرضى الروماتويد وعلاقتها بنشاط المرض ومؤشر العجز وتآكل المفاصل في الأشعة [Added title page title]
Subject(s): Online resources: Available additional physical forms:
  • Issued also as CD
Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Rheumatology and Rehabilitation Summary: Objective: to evaluate Health Related Quality of Life (HRQoL) in Rheumatoid Arthritis (RA) patients, evaluate the effect of early treatment with Disease Modifying Anti-Rheumatic Drugs (DMARDs) on HRQoL and evaluate the effect of treatment adherence and factors affecting it. Results: RA patients had a significantly lower Physical Component Summary (PCS) score than healthy controls (P=0.001). Group A patients had significantly Lower disease activity (P = 0.001), lower MHAQ score (P = 0.001), less x-ray erosions (P = 0.001) and significantly higher PCS (P = 0.001) and Mental Component Summary (MCS) (P = 0.003) scores than group B patients. Adherent patients had significantly less disease activity (P<0.001), less joint destruction in X-ray (P=0.02) and lower MHAQ score (P<0.001) than non-adherent patients. Also PCS and MCS scores were significantly higher in adherent patients (P = 0.001 and 0.042 respectively). Factors that were associated with lower adherence rate were: younger age (P = 0.008), rural residence (P = 0.045), lack of patients{u2019} awareness about their condition (P = 0.001), fear from medication side effects (P = 0.006), lack of belief in medication effectiveness (P = 0.001), occurrence of medication side effects (P = 0.027), absence of medical insurance (P = 0.049) and difficult ambulation (P = 0.039). Conclusion: RA can enormously affect HRQoL. Early diagnosis and treatment by a rheumatologist within the first 6 months of disease onset together with adherence to DMARDs appear to significantly improve outcome and quality of life in RA patients.
Tags from this library: No tags from this library for this title. Log in to add tags.
Star ratings
    Average rating: 0.0 (0 votes)
Holdings
Item type Current library Home library Call number Copy number Status Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.32.M.Sc.2015.Ay.H (Browse shelf(Opens below)) Not for loan 01010110068848000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.32.M.Sc.2015.Ay.H (Browse shelf(Opens below)) 68848.CD Not for loan 01020110068848000
Browsing المكتبة المركزبة الجديدة - جامعة القاهرة shelves Close shelf browser (Hides shelf browser)
No cover image available
No cover image available
No cover image available
No cover image available
No cover image available
No cover image available
No cover image available
Cai01.11.32.M.Sc.2014.Ra.E Estimation of 25 hydroxyvitamin D level and vitamin D deficiency in Juvenile Idiopathic Arthritis (JIA) patients and its relation to disease activity / Cai01.11.32.M.Sc.2014.Ra.E Estimation of 25 hydroxyvitamin D level and vitamin D deficiency in Juvenile Idiopathic Arthritis (JIA) patients and its relation to disease activity / Cai01.11.32.M.Sc.2015.Ay.H Health related quality of life in rheumatoid arthritis patients : Correlation with disease activity, disability index and radiological damage / Cai01.11.32.M.Sc.2015.Ay.H Health related quality of life in rheumatoid arthritis patients : Correlation with disease activity, disability index and radiological damage / Cai01.11.32.M.Sc.2015.Di.G Genetic study of three-prime repair exonuclease (trex1) in the susceptibility to systemic lupus erythematosus (SLE) among Egyptian patients / Cai01.11.32.M.Sc.2015.Di.G Genetic study of three-prime repair exonuclease (trex1) in the susceptibility to systemic lupus erythematosus (SLE) among Egyptian patients / Cai01.11.32.M.Sc.2015.Sa.B ِBehcet's disease : Patterns and disease subsets In patients admitted to rheumatology and rehabilitation department /

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Rheumatology and Rehabilitation

Objective: to evaluate Health Related Quality of Life (HRQoL) in Rheumatoid Arthritis (RA) patients, evaluate the effect of early treatment with Disease Modifying Anti-Rheumatic Drugs (DMARDs) on HRQoL and evaluate the effect of treatment adherence and factors affecting it. Results: RA patients had a significantly lower Physical Component Summary (PCS) score than healthy controls (P=0.001). Group A patients had significantly Lower disease activity (P = 0.001), lower MHAQ score (P = 0.001), less x-ray erosions (P = 0.001) and significantly higher PCS (P = 0.001) and Mental Component Summary (MCS) (P = 0.003) scores than group B patients. Adherent patients had significantly less disease activity (P<0.001), less joint destruction in X-ray (P=0.02) and lower MHAQ score (P<0.001) than non-adherent patients. Also PCS and MCS scores were significantly higher in adherent patients (P = 0.001 and 0.042 respectively). Factors that were associated with lower adherence rate were: younger age (P = 0.008), rural residence (P = 0.045), lack of patients{u2019} awareness about their condition (P = 0.001), fear from medication side effects (P = 0.006), lack of belief in medication effectiveness (P = 0.001), occurrence of medication side effects (P = 0.027), absence of medical insurance (P = 0.049) and difficult ambulation (P = 0.039). Conclusion: RA can enormously affect HRQoL. Early diagnosis and treatment by a rheumatologist within the first 6 months of disease onset together with adherence to DMARDs appear to significantly improve outcome and quality of life in RA patients.

Issued also as CD

There are no comments on this title.

to post a comment.

Click on an image to view it in the image viewer

Local cover image