header
Local cover image
Local cover image
Image from OpenLibrary

Relation between resistin, obesity associated inflammation and atherosclerosis in male albino rats / Seham Mohamed Sayed ; Supervised Maha Mohamed Sabry , Laila Ahmed Rashed , Amal Fahmy Tawadrous

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Seham Mohamed Sayed , 2016Description: 218 P. : charts , facsimiles ; 25cmOther title:
  • العلاقة بين الريزيستين والإلتهاب المصاحب للسمنة وتصلب الشرايين فى ذكور الفئران البيضاء [Added title page title]
Subject(s): Online resources: Available additional physical forms:
  • Issued also as CD
Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Physiology Summary: Background: Obesity is a primary risk factor for atherosclerosis. Adipokines are cytokines, secreted by adipose tissue that couple the regulation of lipid accumulation, inflammation, and atherogenesis, and therefore may serve to link obesity with cardiovascular disorders. Resistin is a cysteine rich adipokine with proinflammatory effects, atherogenic properties and has a potential role in the regulation of adipocyte and macrophage function . Increasing evidence suggests that PPAR-Þ activation is an important regulator of resistin protein, so that it may be a therapeutic target in the treatment of atherosclerotic complication. Objective: The present work aimed to study: 1) The effect of induction of obesity and atherosclerosis on serum resistin and its gene expression in adipose tissue. 2) The relation between resistin and change in body weight, dyslipidemia and inflammatory markers. 3) The interplay between PPAR-Þ agonist and resistin, its impact on lipid profile and inflammatory markers in both models. 4) The histopathological changes in rat aortic strips in all studied groups
Tags from this library: No tags from this library for this title. Log in to add tags.
Star ratings
    Average rating: 0.0 (0 votes)
Holdings
Item type Current library Home library Call number Copy number Status Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.30.M.Sc.2016.Se.R (Browse shelf(Opens below)) Not for loan 01010110069168000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.30.M.Sc.2016.Se.R (Browse shelf(Opens below)) 69168.CD Not for loan 01020110069168000

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Physiology

Background: Obesity is a primary risk factor for atherosclerosis. Adipokines are cytokines, secreted by adipose tissue that couple the regulation of lipid accumulation, inflammation, and atherogenesis, and therefore may serve to link obesity with cardiovascular disorders. Resistin is a cysteine rich adipokine with proinflammatory effects, atherogenic properties and has a potential role in the regulation of adipocyte and macrophage function . Increasing evidence suggests that PPAR-Þ activation is an important regulator of resistin protein, so that it may be a therapeutic target in the treatment of atherosclerotic complication. Objective: The present work aimed to study: 1) The effect of induction of obesity and atherosclerosis on serum resistin and its gene expression in adipose tissue. 2) The relation between resistin and change in body weight, dyslipidemia and inflammatory markers. 3) The interplay between PPAR-Þ agonist and resistin, its impact on lipid profile and inflammatory markers in both models. 4) The histopathological changes in rat aortic strips in all studied groups

Issued also as CD

There are no comments on this title.

to post a comment.

Click on an image to view it in the image viewer

Local cover image