Immunomodulatory effect of packed red blood cells transfusion in premature neonates at different postnatal ages / Mustafa Mahmoud Abdelkader Nadac ; Supervised Lamiaa Mohamed Abdelfattah Mohsen , Hala Yousef Ibrahem , Hala Aly Abdelrahman
Material type: TextLanguage: English Publication details: Cairo : Mustafa Mahmoud Abdelkader Nada , 2016Description: 145 P. : charts , facsimiles ; 25cmOther title:- التأثيرات المناعية على نقل كرات الدم المكدسة فى الاطفال المبتسرين ناقصى النمو فى مختلف الاعمار بعد الولادة [Added title page title]
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Item type | Current library | Home library | Call number | Copy number | Status | Date due | Barcode | |
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Thesis | قاعة الرسائل الجامعية - الدور الاول | المكتبة المركزبة الجديدة - جامعة القاهرة | Cai01.11.28.M.Sc.2016.Mu.I (Browse shelf(Opens below)) | Not for loan | 01010110069591000 | |||
CD - Rom | مخـــزن الرســائل الجـــامعية - البدروم | المكتبة المركزبة الجديدة - جامعة القاهرة | Cai01.11.28.M.Sc.2016.Mu.I (Browse shelf(Opens below)) | 69591.CD | Not for loan | 01020110069591000 |
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Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics
The aim of the study is to detect the increase in proinflammatory cytokine (interleukin- 8) and marker of endothelial activation (soluble intercellular adhesion molecule- 1), as manifestation of transfusion-related immunomodulation in preterm neonates at different postnatal ages. Results: In group 1 neonates the post-transfusion levels of IL-8 was higher than the pre-transfusion levels with no statistical significance yet there was a trend. In group 2 neonates the post-transfusion IL-8 levels was higher than the pre-transfusion levels and the difference was not statistically significant. In group 1 & 2 neonates, there was no statistical significance between the pre- and post-transfusion sICAM-1 levels. There was a positive correlation between the post-transfusion level of IL8 and its level in packed red blood cells (PRBCs) bags in both groups. This correlation was significant in group 2 and was not significant, but yet there was a trend in group 1. And there was a significant positive correlation between post-transfusion levels of IL-8 and sICAM-1 in group 1 neonates.
Issued also as CD
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