Estimation of plasma microrna- 192 in patients with diabetic nephropathy / Ghada Rabie Abdelaziz Ahmed ; Supervised Mohamed Gamal Eldin Saadi , Amr Abdelhady Elmeligi , Mervat Saad Elansary
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TextLanguage: English Publication details: Cairo : Ghada Rabie Abdelaziz Ahmed , 2015Description: 228 P. : charts , facsimiles 25cmOther title: - قياس مستوي الحمض النووي الريبوزومي المصغر- ١٩٢ فى البلازما لدي مرضى اعتلال الكلى السكري [Added title page title]
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قاعة الرسائل الجامعية - الدور الاول | المكتبة المركزبة الجديدة - جامعة القاهرة | Cai01.11.18.Ph.D.2015.Gh.E (Browse shelf(Opens below)) | Not for loan | 01010110069592000 | ||
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مخـــزن الرســائل الجـــامعية - البدروم | المكتبة المركزبة الجديدة - جامعة القاهرة | Cai01.11.18.Ph.D.2015.Gh.E (Browse shelf(Opens below)) | 69592.CD | Not for loan | 01020110069592000 |
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Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Internal Medicine
Diabetic nephropathy (DN) is the leading cause of kidney failure. This study was designed to evaluate the blood level of microRNA-192 and its relation to the disease severity in patients with type2 diabetes mellitus with and without evidence of diabetic nephropathy evidenced by presence of albuminuria expressed by urinary Albumin/Creatinine ratio. We found that microRNA-192 levels were significantly higher in patients with lower eGFR and higher Albumin/Creatinine ratios. Our findings may help to find a new marker for detection of diabetic nephropathy and this could be used in the future as a novel therapeutic approach for treatment of diabetic nephropathy.
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