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Opioid switching to alternative strong opioids in cancer patients experiencing severe pain or untolerable side effects / Mohamed Ahmed Mousa Mohamed ; Supervised Salah Eldin Ahmed Ibrahim , Mohamed Mohamed Mosaad Elwaseef

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Mohamed Ahmed Mousa Mohamed , 2016Description: 98 P. : charts ; 30cmOther title:
  • التبديل الافيونى للعقارات الافيونية القوية فى مرضى السرطان الذين يعانون من آلام شديدة أو أعراض جانبية غير محتملة [Added title page title]
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Dissertation note: Thesis (Ph.D.) - Cairo University - National Cancer Institute - Department of Anesthesia and Pain relief Summary: The aim of this work is to compare opioid shifting results from morphine to hydromorphone, oxycodone and fentanyl regarding analgesia and side effects in cancer pain patients. Opioid rotation involves changing from one opioid to another or one route of administration to another, using correct equianalgesic conversion techniques to achieve better and analgesia and or fewer side effects the strategy appears to work because of significant interindividual variations in response to both analgesic activity and toxicity although there are many retrospective studies. few prospective controlled trials of opioid rotation have been published the practical and theortical advantages of opioid rotation include improved analgesia, reduced side effects, cost reduction, and improved compliance. Disadvantages include problems related to inaccurate conversion tables, limited availability of certain opioid formulations, drug interactions, and the possibility of increased expense. Weighting the advantages and disadvantages is essential prior to making a decision about opioid rotation selection.
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Item type Current library Home library Call number Copy number Status Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.19.01.Ph.D.2016.Mo.O (Browse shelf(Opens below)) Not for loan 01010110070476000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.19.01.Ph.D.2016.Mo.O (Browse shelf(Opens below)) 70476.CD Not for loan 01020110070476000

Thesis (Ph.D.) - Cairo University - National Cancer Institute - Department of Anesthesia and Pain relief

The aim of this work is to compare opioid shifting results from morphine to hydromorphone, oxycodone and fentanyl regarding analgesia and side effects in cancer pain patients. Opioid rotation involves changing from one opioid to another or one route of administration to another, using correct equianalgesic conversion techniques to achieve better and analgesia and or fewer side effects the strategy appears to work because of significant interindividual variations in response to both analgesic activity and toxicity although there are many retrospective studies. few prospective controlled trials of opioid rotation have been published the practical and theortical advantages of opioid rotation include improved analgesia, reduced side effects, cost reduction, and improved compliance. Disadvantages include problems related to inaccurate conversion tables, limited availability of certain opioid formulations, drug interactions, and the possibility of increased expense. Weighting the advantages and disadvantages is essential prior to making a decision about opioid rotation selection.

Issued also as CD

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