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Association between Angiotensin I-Converting Enzyme (ACE) gene polymorphism And Vaso-Occlusive Crisis (VOC) In Egyptian sickle cell disease patients / Mahinour Wageeh Abdelhameed Eldemerdash ; supervised Heba Mahmoud Gouda , Mona Kamal Elghamrawy , Maha Hamdi Elsissy

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Mahinour Wageeh Abdelhameed Eldemerdash , 2016Description: 141 p. : charts , facsimiles ; 25cmOther title:
  • الربط بين تعدد الاشكال الوراثية لجين الانزيم المحول للانجيوتنسين و ازمة انسداد الأوعية فى مرضى فقر الدم المنجلى المصريين [Added title page title]
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Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology Summary: Background and objectives: SCD is one of a group of conditions known as hemoglobinopathies.Hemoglobinopathies are characterized by reduced production of normal hemoglobin protein and/or production of abnormal hemoglobin protein. The frequency of the various genotypes of the ACE I/D polymorphism among SCD patients is not established, with geographic variations. The aim of the study is to detect the possible association between angiotensin I-converting enzyme (ACE) gene polymorphism and vaso-occlusive crisis (VOC) in Egyptian Sickle cell Disease patients. Method: The present study was conducted on 100 patients with Sickle cell disease, Their ages ranged between 1-38 years. One hundred age and sex matched healthy volunteers were included in the current study as a control group. Detection of angiotensin I-converting enzyme (ACE) gene polymorphism by multiplex polymerase chain reaction (Multiplex PCR) was performed.Conclusion:It is not evident in our study that there is an association between angiotensin I-converting enzyme (ACE) gene polymorphism and vaso- occlusive crisis (VOC) in Egyptian Sickle cell Disease patients
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Item type Current library Home library Call number Copy number Status Date due Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.07.M.Sc.2016.Ma.A (Browse shelf(Opens below)) Not for loan 01010110070714000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.07.M.Sc.2016.Ma.A (Browse shelf(Opens below)) 70714.CD Not for loan 01020110070714000

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology

Background and objectives: SCD is one of a group of conditions known as hemoglobinopathies.Hemoglobinopathies are characterized by reduced production of normal hemoglobin protein and/or production of abnormal hemoglobin protein. The frequency of the various genotypes of the ACE I/D polymorphism among SCD patients is not established, with geographic variations. The aim of the study is to detect the possible association between angiotensin I-converting enzyme (ACE) gene polymorphism and vaso-occlusive crisis (VOC) in Egyptian Sickle cell Disease patients. Method: The present study was conducted on 100 patients with Sickle cell disease, Their ages ranged between 1-38 years. One hundred age and sex matched healthy volunteers were included in the current study as a control group. Detection of angiotensin I-converting enzyme (ACE) gene polymorphism by multiplex polymerase chain reaction (Multiplex PCR) was performed.Conclusion:It is not evident in our study that there is an association between angiotensin I-converting enzyme (ACE) gene polymorphism and vaso- occlusive crisis (VOC) in Egyptian Sickle cell Disease patients

Issued also as CD

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