Potential application of diffusion weighted imaging (DWIs) in characterization of parotid tumors / Ayman Mohamed Abdelmottelb Aly Nada ; Supervised Ahmed Mohamed Shokry , Ayman Abdelwahab Amin , Ayman Abdelhamid Elbasmy

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Ayman Mohamed Abdelmottelb Aly Nada

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TextLanguage: English Publication details: Cairo : Ayman Mohamed Abdelmottelb Aly Nada , 2016Description: 213 P. : charts , facsimile ; 25cmOther title:

دور التصوير بالرنين المغناطيسى الانتشارى الموزون فى تمييز أورام الغدة النكافية [Added title page title]

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Dissertation note: Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Radio-diagnosis Summary: Purpose: To investigate the potential application of new MRI techniques with emphasis to diffusion weighted echo planar imaging (DW-EPI) in characterization and differentiation between benign and malignant parotid gland tumors. Results: The mean ADC value of the normal parotid gland was found to be 1.12 ± 0.12 x 10-3mm²/s. The mean ADC value for benign tumors was 1.16 ± 0.31 x 10⁻³mm2/s and mean relative ADC value was 1.6, while the mean ADC and relative ADC values of malignant tumors found to be 0.82 x 10⁻³mm²/s and 1.04 respectively. However overlap still exists. ROC analysis produced cut off values of 0.93 x 10-3 mm2/sec and 1.01 between benign and malignant lesions with sensitivity 72.09% & 89% and specificity 82% & 86% for the absolute and relative ADC values respectively. Conclusion: Determining whether a parotid gland tumor is benign or malignant on the basis of combining morphologic features and DWIs & ADC measurements in a diagnostic noninvasive approach are very promising and might decrease number of unnecessary invasive procedures e.g. biopsies or inappropriate extensive surgical approaches for benign parotid lesions

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Item type	Current library	Home library	Call number	Copy number	Status	Date due	Barcode
Thesis	قاعة الرسائل الجامعية - الدور الاول	المكتبة المركزبة الجديدة - جامعة القاهرة	Cai01.11.31.Ph.D.2016.Ay.P (Browse shelf(Opens below))		Not for loan		01010110070693000
CD - Rom	مخـــزن الرســائل الجـــامعية - البدروم	المكتبة المركزبة الجديدة - جامعة القاهرة	Cai01.11.31.Ph.D.2016.Ay.P (Browse shelf(Opens below))	70693.CD	Not for loan		01020110070693000

Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Radio-diagnosis

Purpose: To investigate the potential application of new MRI techniques with emphasis to diffusion weighted echo planar imaging (DW-EPI) in characterization and differentiation between benign and malignant parotid gland tumors. Results: The mean ADC value of the normal parotid gland was found to be 1.12 ± 0.12 x 10-3mm²/s. The mean ADC value for benign tumors was 1.16 ± 0.31 x 10⁻³mm2/s and mean relative ADC value was 1.6, while the mean ADC and relative ADC values of malignant tumors found to be 0.82 x 10⁻³mm²/s and 1.04 respectively. However overlap still exists. ROC analysis produced cut off values of 0.93 x 10-3 mm2/sec and 1.01 between benign and malignant lesions with sensitivity 72.09% & 89% and specificity 82% & 86% for the absolute and relative ADC values respectively. Conclusion: Determining whether a parotid gland tumor is benign or malignant on the basis of combining morphologic features and DWIs & ADC measurements in a diagnostic noninvasive approach are very promising and might decrease number of unnecessary invasive procedures e.g. biopsies or inappropriate extensive surgical approaches for benign parotid lesions

Issued also as CD

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