Maternal erythrocyte alloimmunization as a cause of hemolytic disease of newborn / Nada Hassan Mahmoud Elkousy ; Supervised Mohamed Elsayed Hashem , Sherif Elanwary Abdelmoneim , Maha Hamdi Elsissy

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics

Neonatal hyperbilirubinemia is the most common clinical condition in the newborn requiring evaluation and management and remains a frequent reason for hospital readmission during the first week of postnatal life. Mostly it is a benign postnatal transitional phenomenon of no overt clinical effect. It describes a serum total bilirubin level that exceeds the 95th percentile for the infant{u2019}s age in that population. It is classified to physiological and pathological jaundice, Jaundice in healthy, full term newborns has been termed physiologic because hyperbilirubinemia occurs universally in neonates; total serum bilirubin concentration usually peaks at 5 to 12 mg/dl on the second or third day after birth (kristin et al., 2000). It is considered pathologic if it presents within the first 24 hours after birth, the total serum bilirubin level rises by more than 5 mg / dL per day or is higher than 17 mg / dL or an infant has signs and symptoms suggestive of serious illness

Issued also as CD