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Association between polymorphism of some myogenic regulatory factors and growth traits in bovine / Ismaiel Mostafa Ahmad Ali ; Supervised Elsaid Thabet Awad , Samy Ahmad Abdelaziz , Mohamad Ali Ahmad Warda

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Ismaiel Mostafa Ahmad Ali , 2016Description: 118 P. : charts , facsimiles ; 25cmOther title:
  • الأرتباط و العلاقه بين تعدد الأشكال الجينيه لبعض جينات العوامل المنظمه للعضلات و النمو فى الماشيه [Added title page title]
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Dissertation note: Thesis (Ph.D.) - Cairo University - Faculty of Veterinary Medicine - Department of Biochemistry and Chemistry of Nutrition Summary: The MyoD family of myogenic regulatory factors (MRFs) include several genes such as Myogenin (MyoG) and Myogenic Factor 5 (MYF5) that have the potential to influence economically important traits in beef cattle. The objective of the present study were to estimate the allele and genotype frequencies of the (MyoG) and (MYF5) genes in cattle and buffalo in Egypt and to determine the effects of these polymorphisms on some growth traits in the studied breeds. Genomic DNA was extracted from whole blood of 200 animals including Friesian cattle and buffalo. PCR-SSCP technique was used to genotype (MyoG) and (MYF5). Three genotypes were determined for MyoG exon-1 locus (BB, AB and AC) and two genotypes for MyoG exon- 1and intron-1 locus (AA and AB). Significant positive association were found between MyoG exon-1 AB genotype in Friesian cattle with weight at 6 months (W6) and average daily gain (ADG). For MyoG exon-1and intron-1 locus, the AA genotype showed positive effect on (ADG) in Friesian cattle. For MYF5 gene, exon-2 was monomorphic while three genotypes were determined for MYF5 intron-1 locus (BB, AB and AC) and four genotypes for intron-2 and exon-3 locus (AA, AB, AC and AD). Significant positive association was found between MYF5 intron-1 BB genotype in Egyptian buffalo with (W6) and (ADG). For intron-2 and exon-3 locus, the AD genotype in Friesian cattle and the AB genotype in Egyptian buffalo showed positive effect on (W6) and (ADG). These results could be included into marker assisted selection programs to improve the productivity in these breed
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Item type Current library Home library Call number Copy number Status Date due Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.10.04.Ph.D.2016.Is.A (Browse shelf(Opens below)) Not for loan 01010110071178000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.10.04.Ph.D.2016.Is.A (Browse shelf(Opens below)) 71178.CD Not for loan 01020110071178000

Thesis (Ph.D.) - Cairo University - Faculty of Veterinary Medicine - Department of Biochemistry and Chemistry of Nutrition

The MyoD family of myogenic regulatory factors (MRFs) include several genes such as Myogenin (MyoG) and Myogenic Factor 5 (MYF5) that have the potential to influence economically important traits in beef cattle. The objective of the present study were to estimate the allele and genotype frequencies of the (MyoG) and (MYF5) genes in cattle and buffalo in Egypt and to determine the effects of these polymorphisms on some growth traits in the studied breeds. Genomic DNA was extracted from whole blood of 200 animals including Friesian cattle and buffalo. PCR-SSCP technique was used to genotype (MyoG) and (MYF5). Three genotypes were determined for MyoG exon-1 locus (BB, AB and AC) and two genotypes for MyoG exon- 1and intron-1 locus (AA and AB). Significant positive association were found between MyoG exon-1 AB genotype in Friesian cattle with weight at 6 months (W6) and average daily gain (ADG). For MyoG exon-1and intron-1 locus, the AA genotype showed positive effect on (ADG) in Friesian cattle. For MYF5 gene, exon-2 was monomorphic while three genotypes were determined for MYF5 intron-1 locus (BB, AB and AC) and four genotypes for intron-2 and exon-3 locus (AA, AB, AC and AD). Significant positive association was found between MYF5 intron-1 BB genotype in Egyptian buffalo with (W6) and (ADG). For intron-2 and exon-3 locus, the AD genotype in Friesian cattle and the AB genotype in Egyptian buffalo showed positive effect on (W6) and (ADG). These results could be included into marker assisted selection programs to improve the productivity in these breed

Issued also as CD

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