header
Image from OpenLibrary

Serum biomarkers and transient elastography versus histopathology for assessment of post living donor liver transplantation (LDLT) HCV recurrence / Amr Mohamed Farag Elsayed ; Supervised Ayman Yosry Abdelrehim , Mohamed Said Abdelaziz , Olfat Gamil Shaker

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Amr Mohamed Farag Elsayed , 2016Description: 150 P. : charts ; 25cmOther title:
  • استخدام الدلالات البيوكيميائية السيرولوجية و الفيبروسكان مقارنة بالفحص الهستوباثولوجى لتقييم حدوث تليف الكبد الناتج عن فيروس سى فى المرضى بعد زراعة الكبد من متبرعين أحياء [Added title page title]
Subject(s): Available additional physical forms:
  • Issued also as CD
Dissertation note: Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Tropical Medicine Summary: This is a retrospective and prospective study that aimed to predict fibrosis in HCV infected liver transplant recipients (25 recipients) with serum markers and TE( Fibroscan )and to validate the diagnostic accuracy of these noninvasive methods in comparison with liver biopsy. In our series none of the recipients who developed clinical HCV recurrence developed allograft cirrhosis over mean follow up period of 16.8 months and 92% of our patients developed only mild fibrosis (F1).Non invasive indices showed variable accuracy in prediction of fibrosis; Fib4 was not accurate in prediction of fibrosis while AST/ALT ratio and Age/Plt indices showed rough correlation with fibrosis stages assessed by Metavir score with no adequate results to conclude its ability to predict precisely each stage. APRI and Hyaluronic (HA) were able to predict fibrosis adequately in comparison with liver biopsy. Tissue elasticity was moderately able to predict fibrosis. Howevere large sample volume could help in proper validation as well as variability of stages of fibrosis among studied population
Tags from this library: No tags from this library for this title. Log in to add tags.
Star ratings
    Average rating: 0.0 (0 votes)
Holdings
Item type Current library Home library Call number Copy number Status Date due Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.33.Ph.D.2016.Am.S (Browse shelf(Opens below)) Not for loan 01010110071251000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.33.Ph.D.2016.Am.S (Browse shelf(Opens below)) 71251.CD Not for loan 01020110071251000

Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Tropical Medicine

This is a retrospective and prospective study that aimed to predict fibrosis in HCV infected liver transplant recipients (25 recipients) with serum markers and TE( Fibroscan )and to validate the diagnostic accuracy of these noninvasive methods in comparison with liver biopsy. In our series none of the recipients who developed clinical HCV recurrence developed allograft cirrhosis over mean follow up period of 16.8 months and 92% of our patients developed only mild fibrosis (F1).Non invasive indices showed variable accuracy in prediction of fibrosis; Fib4 was not accurate in prediction of fibrosis while AST/ALT ratio and Age/Plt indices showed rough correlation with fibrosis stages assessed by Metavir score with no adequate results to conclude its ability to predict precisely each stage. APRI and Hyaluronic (HA) were able to predict fibrosis adequately in comparison with liver biopsy. Tissue elasticity was moderately able to predict fibrosis. Howevere large sample volume could help in proper validation as well as variability of stages of fibrosis among studied population

Issued also as CD

There are no comments on this title.

to post a comment.