Association of Alpha B-Crystallin (CRYAB) genotypes with breast cancer / Ayam Rasheed Alshaheen ; Supervised Abdou Osman Abdelhamid , Abd Allah Awidi , Heba Mohamed Kamal

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Ayam Rasheed Alshaheen

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TextLanguage: English Publication details: Cairo : Ayam Rasheed Alshaheen , 2016Description: 78 P. : charts , facsimiles ; 25cmOther title:

بسرطان الثدى (CRYAB)ارتباط الأنماط الوراثية ألفا كريستالين - ب [Added title page title]

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Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Biotechnology Summary: Breast cancer is the most common cancer that affects women worldwide with an estimated 1.3 million new cases diagnosed annually. Mammalian alpha B-crystallin (CRYAB) is a member of the small heat-shock protein (sHSP) family and a molecular chaperone continuously expressed in various tissues.This review focus on Evaluate the association of polymorphic genotypes of CRYAB with breast cancer, in this study we have selected two SNPs of the CRYAB gene, and investigated the associations with the susceptibility to breast cancer .the present study proved Alleles CRYAB C-802G (rs14133) were significantly associated with a higher susceptibility to breast cancer. this provides will use in biomarker to help in prevent and treatment breast cancer

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Item type	Current library	Home library	Call number	Copy number	Status	Date due	Barcode
Thesis	قاعة الرسائل الجامعية - الدور الاول	المكتبة المركزبة الجديدة - جامعة القاهرة	Cai01.12.25.M.Sc.2016.Ay.A (Browse shelf(Opens below))		Not for loan		01010110071479000
CD - Rom	مخـــزن الرســائل الجـــامعية - البدروم	المكتبة المركزبة الجديدة - جامعة القاهرة	Cai01.12.25.M.Sc.2016.Ay.A (Browse shelf(Opens below))	71479.CD	Not for loan		01020110071479000

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Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Biotechnology

Breast cancer is the most common cancer that affects women worldwide with an estimated 1.3 million new cases diagnosed annually. Mammalian alpha B-crystallin (CRYAB) is a member of the small heat-shock protein (sHSP) family and a molecular chaperone continuously expressed in various tissues.This review focus on Evaluate the association of polymorphic genotypes of CRYAB with breast cancer, in this study we have selected two SNPs of the CRYAB gene, and investigated the associations with the susceptibility to breast cancer .the present study proved Alleles CRYAB C-802G (rs14133) were significantly associated with a higher susceptibility to breast cancer. this provides will use in biomarker to help in prevent and treatment breast cancer

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