Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of General Surgery

Surgical site infection (SSI) is the most commonly reported nosocomial infection. Surgical site infections are responsible for increase in cost, morbidity, and mortality related to surgical operations. Surveillance with information feedback to surgeons and other medical staff has been shown to be an important element in the overall strategy to reduce the numbers of SSIs. To determine the incidence and factors responsible for, causative micro-organisms and effective antibiotics for surgical site infections following emergency abdominal operations at Kasr Alaini emergency Hospital. A total of 42 patients were enrolled in the current study and were prospectively followed till the tenth day post-operatively. Data collection sheets were filled in for all the patients. If any symptom or sign of infection appear during this period then proper investigation was instituted for the diagnosis of infection and to assess the type and severity of the infection. If any collection of pus identified it was drained out and sent for culture and sensitivity test. Proper antibiotic was given to every patient both preoperative and post-operative periods. Antibiotic was changed where necessary after getting the report of culture and sensitivity test. Surveillance of SSIs in the current study revealed an SSI incidence of 42.9%. The most frequent organisms detected by wound swab cultures were E. coli (41.6 %), followed by Klebsiella and CONS, with the emergence of resistant strains like MDR, AMPC, ESBL strains. Sensitivity to antiobiotics showed colistin, polymyxin B, vancomycin and tigecycline to be fully functional, next in sensitivity was piperacillin tazobactam, then meropenem, followed by imipenem and amikacin. SSI was found to be increased with the advancement in age

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