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Effect of intracoronary (IC) tirofiban following aspiration thrombectomy on infarct size, in patients with large anterior STEMI undergoing primary PCI / Ahmed Mustafa Abdelsalam Mohamed ; Supervised Wael Mohamed Elnaggar , Mohamed Abdelmeguid Mahdy , Sameh Alkaffas

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Ahmed Mustafa Abdelsalam Mohamed , 2016Description: 164 Leaves : charts , facsimiles ; 30cmOther title:
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Dissertation note: Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Cardiology Summary: Evaluable MRI results at 30 days where present in only 40 of 50 patients (80%), with the most common reasons for missing data being patient re-infarction prior to 30 days and inability to tolerate the procedure. Patients randomized to IC Tirofiban compared with no IC Tirofiban had a significant reduction at 30 days infarct size (median, 15451 mm3 - IQR, 17404 mm3 - n=20) vs (median, 43828 mm3 - IQR, 49599 mm3 - n=20) P value= 0.002. Patients randomized to IC Tirofiban compared with no IC Tirofiban had no significant in MBG post PCI (P value= 0.67). In patients with large anterior STEMI presenting early after symptom onset and undergoing primary PCI, infarct size at 30 days was significantly reduced by bolus IC Tirofiban delivered to the infarct lesion site following manual Aspiration Thrombectomy. There is no significance in MACE at 30 days between patients received bolus IC Tirofiban and patients who did not receive (P value= 0.723).
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Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.04.Ph.D.2016.Ah.E (Browse shelf(Opens below)) Not for loan 01010110071995000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.04.Ph.D.2016.Ah.E (Browse shelf(Opens below)) 71995.CD Not for loan 01020110071995000

Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Cardiology

Evaluable MRI results at 30 days where present in only 40 of 50 patients (80%), with the most common reasons for missing data being patient re-infarction prior to 30 days and inability to tolerate the procedure. Patients randomized to IC Tirofiban compared with no IC Tirofiban had a significant reduction at 30 days infarct size (median, 15451 mm3 - IQR, 17404 mm3 - n=20) vs (median, 43828 mm3 - IQR, 49599 mm3 - n=20) P value= 0.002. Patients randomized to IC Tirofiban compared with no IC Tirofiban had no significant in MBG post PCI (P value= 0.67). In patients with large anterior STEMI presenting early after symptom onset and undergoing primary PCI, infarct size at 30 days was significantly reduced by bolus IC Tirofiban delivered to the infarct lesion site following manual Aspiration Thrombectomy. There is no significance in MACE at 30 days between patients received bolus IC Tirofiban and patients who did not receive (P value= 0.723).

Issued also as CD

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