Molecular characterization of the P7 protein of the hepatitic C virus as intracellular modulator and direct antiviral target / Noha Samir Farag ; Supervised Hans Georg Breitinger , Mohammed Elazizi
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TextLanguage: English Publication details: Cairo : Noha Samir Farag , 2014Description: 150 Leaves : charts , facsimiles ; 30cmSubject(s): Dissertation note: Thesis (Ph.D.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Microbiology Summary: Hepatitis C virus (HCV) infection is a major cause of acute and chronic liver disease with more than 3% of the world's population infected and more than 170 million chronic carriers at risk of developing liver cirrhosis and/or liver cancer. Although new treatment have been introduced, the search for new anti-viral targets is still a major necessity especially in Egypt where 18% of the population is infected. HCV P7, a 63-residue transmembrane protein belonging to the family of viropoins has been introduced recently as a new antiviral target. The precise mechanism as to how p7 functions as an ion channcel and its contribution to the virus life cycle is still elusive
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Thesis
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قاعة الثقاقات الاجنبية - الدور الثالث | المكتبة المركزبة الجديدة - جامعة القاهرة | Cai01.34.Ph.D.2014.No.M (Browse shelf(Opens below)) | Not for loan | 01010110072298000 |
Thesis (Ph.D.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Microbiology
Hepatitis C virus (HCV) infection is a major cause of acute and chronic liver disease with more than 3% of the world's population infected and more than 170 million chronic carriers at risk of developing liver cirrhosis and/or liver cancer. Although new treatment have been introduced, the search for new anti-viral targets is still a major necessity especially in Egypt where 18% of the population is infected. HCV P7, a 63-residue transmembrane protein belonging to the family of viropoins has been introduced recently as a new antiviral target. The precise mechanism as to how p7 functions as an ion channcel and its contribution to the virus life cycle is still elusive
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