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N1-linked and C2 linked Melatonin dimers as bivalent ligands targeting dimeric melatonin peceptors / Sarah Adel Ayad Tadros ; Supervised Darius P. Zlotos

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Sarah Adel Ayad Tadros , 2014Description: 165 Leaves : charts ; 30cmSubject(s): Dissertation note: Thesis (M.Sc.) - Garman University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmaceutical Chemistry Summary: G-protein-coupled receptors (GPCRs) constitute the largest cell surface receptor family and are considered drug targets for about 50% of the currently used druge. Rccently , they were show to have the ability to exist as constitutive homo-or heterodimers with different Pharmaceutical and signaling properties whic offers new perrspective for drug design and drug treatment.
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Thesis (M.Sc.) - Garman University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmaceutical Chemistry

G-protein-coupled receptors (GPCRs) constitute the largest cell surface receptor family and are considered drug targets for about 50% of the currently used druge. Rccently , they were show to have the ability to exist as constitutive homo-or heterodimers with different Pharmaceutical and signaling properties whic offers new perrspective for drug design and drug treatment.

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