Possible role of resveratrol and induced pluripotent stem cells : Targeting estradiol and neprilysin pathways in lipopolysacchartide induced alzheimer's disease model / Yasmeen Nasser Bayan ; Supervised Nesrine S. Elsayed , Fawzy Abdelatty
Material type:
Item type | Current library | Home library | Call number | Status | Barcode | |
---|---|---|---|---|---|---|
![]() |
قاعة الثقاقات الاجنبية - الدور الثالث | المكتبة المركزبة الجديدة - جامعة القاهرة | Cai01.34.M.Sc.2014.Ya.P (Browse shelf(Opens below)) | Not for loan | 01010110072262000 |
Thesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmacology and Toxicology
Alzheimer's disease (AD) is an irreversible, proressive neurodegenerative brain disease that slowly destroys memory and thinking skills. It is the most common cause of dementia among older people. One of the most important hallmarks of AD is the presence of amykid beta (AÝ) peptide in the brain that suggests that it is the primary trigger for neuronal loss. Herbal extracts have been studied over the years for their potential therapeutic effect in AD. Resveratrol (RSV), one of the most important phytoestrogens, is considered to be useful as estrogen plays an important role in AD. One of the most important amyloid degrading enzymes is neprilysin (NEP) which plays a major role in degrading AÝ and mainly affected by estrogen
There are no comments on this title.