Silencing of the metastasis-liked gene, AEG-1, using siRNA-loaded cholamine-modified gelatin nanoparticles in the breast carcinoma cell line MCF-7 / Salma Mahmoud Sadek Mohamed Abozeid ; Supervised Khaled Abou Aisha , Rania Mohmmed Hathout
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TextLanguage: English Publication details: Cairo : Salma Mahmoud Sadek Mohamed Abozeid , 2015Description: 69 Leaves : charts , facsimiles ; 30cmSubject(s): Dissertation note: Thesis (M.Sc.) - Garman University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmaceutical Biology Summary: Since the discovery of RNA interence (RNAi), it has been applied in cancer biology to investigate gene mechanisms involved in developing cancerous cells and help designing new therapeutics. Small interfering RNA (siRNA), a small double stranded nucleotide induces the RNAi machinery inside the cells siRNA therapeutics poses a challenge due to their rapid clearance by nuclease and minimum cellular uptake.
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Thesis
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قاعة الثقاقات الاجنبية - الدور الثالث | المكتبة المركزبة الجديدة - جامعة القاهرة | Cai01.34.M.Sc.2015.Sa.S (Browse shelf(Opens below)) | Not for loan | 01010110072321000 |
Thesis (M.Sc.) - Garman University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmaceutical Biology
Since the discovery of RNA interence (RNAi), it has been applied in cancer biology to investigate gene mechanisms involved in developing cancerous cells and help designing new therapeutics. Small interfering RNA (siRNA), a small double stranded nucleotide induces the RNAi machinery inside the cells siRNA therapeutics poses a challenge due to their rapid clearance by nuclease and minimum cellular uptake.
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