C2- linked dimeric strychnine analogs as bivalent ligands targeting glycine receptors / Maha Magdy Farag Banoub ; Supervised Darius P. Zlotos

By:

Maha Magdy Farag Banoub

Contributor(s):

Darius P. Zlotos []

Material type: Text

TextLanguage: English Publication details: Cairo : Maha Magdy Farag Banoub , 2016Description: 109 Leaves : charts , facsimiles ; 30cmOther title:

مترابطة متناظرات الإستركنين المثنوية كروابط ثنائية التكافؤ تستهدف مستقبلات الجلايسين - C2 [Added title page title]

Subject(s):

Dissertation note: Thesis (M.Sc.) - Garman University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmaceutical Chamistry Summary: Strychnine, the major alkaloid from the plant strychnos nux vomica, exhibits pharmaceutical activity at several neurotransmitter receptors, including a number of ligand-gated ion channels, such as muscle-type and neuronal nicotinic acetylchoilne receptors and glycine receptors (GlyRs). Its major pharmaceutical action is a strong antagonistic activity at GlyRs which are anionic chloride channels that mediate inhibitory synaptic transmission in the spinal cord and brainstem.

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Item type	Current library	Home library	Call number	Status	Date due	Barcode
Thesis	قاعة الثقاقات الاجنبية - الدور الثالث	المكتبة المركزبة الجديدة - جامعة القاهرة	Cai01.34.M.Sc.2016.Ma.C (Browse shelf(Opens below))	Not for loan		01010110072406000

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Thesis (M.Sc.) - Garman University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmaceutical Chamistry

Strychnine, the major alkaloid from the plant strychnos nux vomica, exhibits pharmaceutical activity at several neurotransmitter receptors, including a number of ligand-gated ion channels, such as muscle-type and neuronal nicotinic acetylchoilne receptors and glycine receptors (GlyRs). Its major pharmaceutical action is a strong antagonistic activity at GlyRs which are anionic chloride channels that mediate inhibitory synaptic transmission in the spinal cord and brainstem.

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