header
Image from OpenLibrary

In vitro and in vivo evaluation of different formulations of inactivated newcastle disease virus vaccine / Nehal Kamal Abdelshakour ; Supervised Hussein Ali Hussein , Ayman H. M. El-Deeb , Mohamed Abdel khaleck

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Nehal Kamal Abdelshakour , 2017Description: 103 P. : charts , facsimiles ; 25cmOther title:
  • تقييم تحضيرات مختلفه للقاح المثبط لفيروس النيوكاسل معمليا و داخل الطيور [Added title page title]
Subject(s): Available additional physical forms:
  • Issued also as CD
Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Veterinary Medicine - Department of Virology Summary: In Egypt recent outbreaks reported in NDV-vaccinated flocks and the isolated strain was characterized as velogenic NDV belong to class II genotype VIId. In this study, three inactivated NDV vaccine formulations have been prepared from LaSota (genotype II), genotype VIId NDV strain and combined lasota and genotype VIId of NDV at proportion of 1:1. In a challenge trial the prepared vaccines were evaluated in SPF chickens after challenge with 106 EID50/0.5ml velogenic genotype VII of NDV (NDV-B7-RLQP-CH-EG-12). Results revealed that the vaccines were able to achieve 100 % protection of vaccinated birds. The HI titers were statistically different in combined vaccinated group (Lasota and VIId NDV) compared to other groups. Employing VN test in the collected sera of vaccinated groups confirmed the HI and protection results. Studying of shedding pattern revealed that combined vaccinated group reduced the virus frequency and titer. Histopathological examination of collected organs after challenge indicated the protective effect in vaccinated groups compared to the severe lesion score shown in positive control group. In conclusion, the success of combined vaccine in inducing protection and reduction of shedding after challenge with recent genotype VIId of NDV
Tags from this library: No tags from this library for this title. Log in to add tags.
Star ratings
    Average rating: 0.0 (0 votes)
Holdings
Item type Current library Home library Call number Copy number Status Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.10.17.M.Sc.2017.Ne.I (Browse shelf(Opens below)) Not for loan 01010110072711000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.10.17.M.Sc.2017.Ne.I (Browse shelf(Opens below)) 72711.CD Not for loan 01020110072711000

Thesis (M.Sc.) - Cairo University - Faculty of Veterinary Medicine - Department of Virology

In Egypt recent outbreaks reported in NDV-vaccinated flocks and the isolated strain was characterized as velogenic NDV belong to class II genotype VIId. In this study, three inactivated NDV vaccine formulations have been prepared from LaSota (genotype II), genotype VIId NDV strain and combined lasota and genotype VIId of NDV at proportion of 1:1. In a challenge trial the prepared vaccines were evaluated in SPF chickens after challenge with 106 EID50/0.5ml velogenic genotype VII of NDV (NDV-B7-RLQP-CH-EG-12). Results revealed that the vaccines were able to achieve 100 % protection of vaccinated birds. The HI titers were statistically different in combined vaccinated group (Lasota and VIId NDV) compared to other groups. Employing VN test in the collected sera of vaccinated groups confirmed the HI and protection results. Studying of shedding pattern revealed that combined vaccinated group reduced the virus frequency and titer. Histopathological examination of collected organs after challenge indicated the protective effect in vaccinated groups compared to the severe lesion score shown in positive control group. In conclusion, the success of combined vaccine in inducing protection and reduction of shedding after challenge with recent genotype VIId of NDV

Issued also as CD

There are no comments on this title.

to post a comment.