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Assessment of epicardial adipose tissue thickness in children with familial mediterranean fever / Mai Ahmed Omar Ghoraib ; Supervised Emad Emil Ghobrial , Doaa Mohamed Abdulaziz , Yomna Mohamed Farag

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Mai Ahmed Omar Ghoraib , 2017Description: 122 P. : charts ; 25cmOther title:
  • دراسة سمك الدهون حول القلب فى الأطفال المصابون بحمى البحر المتوسط [Added title page title]
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  • Issued also as CD
Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics Summary: Background: Familial Mediterranean fever (FMF) is an auto inflammatory disease, which is suggested to be associated with increased risk of atherosclerosis. Epicardial adipose tissue (EAT) thickness was used in prediction of atherosclerotic risk in various conditions. The aim of our study was to evaluate EAT thickness of FMF children and to be compared with its level in healthy controls. Methods: Thirty children with FMF and aged between 8-16 years and thirty age-and sex-matched children control group) were included in the study. Different disease characteristics, disease severity, and MEFV gene mutations were recorded. EAT thicknesses was measured by echocardiography using the VIVID 5-ECHO machine probe size number 3. Results: EAT in patients was significantly greater than that of controls (5.21±2.3 mm vs. 2.81±2.96 mm, p=0.001) and was correlated with serum cholesterol level and platelets count (p-value 0.047 and 0.018 respectively). Conclusion: Epicardial adipose tissue thickness was greater in children with FMF than controls. These findings may indicate an increased risk of atherosclerosis in FMF patients
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Item type Current library Home library Call number Copy number Status Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.28.M.Sc.2017.Ma.A (Browse shelf(Opens below)) Not for loan 01010110073082000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.28.M.Sc.2017.Ma.A (Browse shelf(Opens below)) 73082.CD Not for loan 01020110073082000

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics

Background: Familial Mediterranean fever (FMF) is an auto inflammatory disease, which is suggested to be associated with increased risk of atherosclerosis. Epicardial adipose tissue (EAT) thickness was used in prediction of atherosclerotic risk in various conditions. The aim of our study was to evaluate EAT thickness of FMF children and to be compared with its level in healthy controls. Methods: Thirty children with FMF and aged between 8-16 years and thirty age-and sex-matched children control group) were included in the study. Different disease characteristics, disease severity, and MEFV gene mutations were recorded. EAT thicknesses was measured by echocardiography using the VIVID 5-ECHO machine probe size number 3. Results: EAT in patients was significantly greater than that of controls (5.21±2.3 mm vs. 2.81±2.96 mm, p=0.001) and was correlated with serum cholesterol level and platelets count (p-value 0.047 and 0.018 respectively). Conclusion: Epicardial adipose tissue thickness was greater in children with FMF than controls. These findings may indicate an increased risk of atherosclerosis in FMF patients

Issued also as CD

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