CT-urography findings in the follow up of high risk non-muscle invasive bladder cancer / Ahmed Sharawy Kamel ; Supervised Sherif Abdelrahman , Ashraf Mosharafa , Hesham Fathy

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Urology

Introduction : The concept of computed tomography urography is attractive since both the renal parenchyma and urothelium can be evaluated with a single comprehensive examination. This primary use of computed tomography urography potentially also allows shortening the overall duration of the patient{u2019}s schedule for diagnostic evaluation. The necessity to perform a baseline computed tomography urography or intravenous urography once a bladder tumour has been detected is questioned because of the low incidence of significant findings obtained. The incidence of upper tract urothelial carcinomas is low (1.8%), but increases to 7.5% in tumours located in the trigone. The risk of upper tract urothelial carcinomas during follow-up increases in patients with multiple and high-risk tumours. Another role for computed tomography urography is detection of pelvic/retroperitoneal lymphadenopathy which may represent metastases from the bladder transitional cell carcinoma, but-as recent reports point out-may also be due to other causes such as tuberculous lymphadenopathy (in patients who received intravesical (BCG)), reactive (infective) lymphadenopathy, or even lymphoma. Aim of work: The aim of the current study is to evaluate the role of computed tomography urography in the follow up of patients diagnosed with high-risk non-muscle-invasive bladder cancer. In particular, whether computed tomography urography would add valuable information to routine follow up cystoscopy or potentially impact management decisions

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