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Immunochemical studies on nuclear matrix protein (NMP) in patients with chronic hepatitis C / Abdallah Ahmed Elbadry Abdallah Ragab ; Supervised Sanaa Osman Abdallah , Abdelfattah Mohamed Attallah

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Abdallah Ahmed Elbadry Abdallah Ragab , 2017Description: 113 P. : charts , facsimiles ; 25cmOther title:
  • دراسات المناعة الكيميائية على بروتين الغشاء النووى فى مرضى الإلتهاب الكبدى الفيروسى سى المزمن [Added title page title]
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Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Biochemistry Summary: This work is concerned with evaluating the possibility of using nuclear matrix proteins (NMP) as biomarker of liver fibrosis in patients with chronic hepatitis C (CHC). A total of 120 CHC-patients and 33 healthy individuals were included in this study. The target NMP was identified based on SDS-PAGE followed by Western-blot. A single immunoreactive band was identified at 52-kDa corresponding to NMP. The concentration of NMP-52 was found to increase significantly (P<0.05) with the progression of liver fibrosis. Thus, the detection of NMP in different stages of liver fibrosis can serve as a good diagnostic marker. The difference of its levels might be helpful in differential diagnosis of CHC-patients with different fibrotic liver stages
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Item type Current library Home library Call number Copy number Status Date due Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.12.02.M.Sc.2017.Ab.I (Browse shelf(Opens below)) Not for loan 01010110073332000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.12.02.M.Sc.2017.Ab.I (Browse shelf(Opens below)) 73332.CD Not for loan 01020110073332000

Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Biochemistry

This work is concerned with evaluating the possibility of using nuclear matrix proteins (NMP) as biomarker of liver fibrosis in patients with chronic hepatitis C (CHC). A total of 120 CHC-patients and 33 healthy individuals were included in this study. The target NMP was identified based on SDS-PAGE followed by Western-blot. A single immunoreactive band was identified at 52-kDa corresponding to NMP. The concentration of NMP-52 was found to increase significantly (P<0.05) with the progression of liver fibrosis. Thus, the detection of NMP in different stages of liver fibrosis can serve as a good diagnostic marker. The difference of its levels might be helpful in differential diagnosis of CHC-patients with different fibrotic liver stages

Issued also as CD

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