header
Local cover image
Local cover image
Image from OpenLibrary

The possible associated MicroRNAs in Egyptian hepatocellular carcinoma patients infected with hepatitis C virus / Khaled Mohamed Saad Elgeshy ; Supervised Elsayed Tarek Abdelsalam , Abeer Mostafa Ashmawy , Mohammed Ghareeb Mahmoud

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Khaled Mohamed Saad Elgeshy , 2017Description: 148 P. : photographs ; 25cmOther title:
  • الترابط المحتمل بين جزيئات الحمض الريبوزى النووى الدقيقة فى سرطانة الخلية الكبدية للمرضى المصريين المصابين بفيروس التهاب الكبد الوبائى - سى [Added title page title]
Subject(s): Online resources: Available additional physical forms:
  • Issued also as CD
Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Microbiology Summary: Introduction: MiRNA play an important role in carcinogenesis and cancer progression specially those associated with viral infection as HCC through different pathways, one of them Wnt/Ý-catenin pathway. Aim of the work: An attempt to uncover the association between liver-related miRs with Wnt/ Ý- catenin pathway proteins in HCC patients infected with HCV. Methods: Wnt/ Ý-catenin pathway proteins were examined using IHC, total RNA [including miRs] extraction performed on samples from the same patients, real time-PCR was performed on the examined miRs, these data were correlated using SPSS for windows software. Results: 6 out of 13 miRs showed significant correlation with 3 out of 5 Wnt/ Ý-catenin pathway proteins. Conclusion: miR-10a, miR- 30e, miR-106b, miR-125b, miR-148a and miR-215 were highly associated with Wnt/ Ý-catenin pathway in HCC cases infected with HCV
Tags from this library: No tags from this library for this title. Log in to add tags.
Star ratings
    Average rating: 0.0 (0 votes)
Holdings
Item type Current library Home library Call number Copy number Status Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.12.18.M.Sc.2017.Kh.P (Browse shelf(Opens below)) Not for loan 01010110073495000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.12.18.M.Sc.2017.Kh.P (Browse shelf(Opens below)) 73495.CD Not for loan 01020110073495000

Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Microbiology

Introduction: MiRNA play an important role in carcinogenesis and cancer progression specially those associated with viral infection as HCC through different pathways, one of them Wnt/Ý-catenin pathway. Aim of the work: An attempt to uncover the association between liver-related miRs with Wnt/ Ý- catenin pathway proteins in HCC patients infected with HCV. Methods: Wnt/ Ý-catenin pathway proteins were examined using IHC, total RNA [including miRs] extraction performed on samples from the same patients, real time-PCR was performed on the examined miRs, these data were correlated using SPSS for windows software. Results: 6 out of 13 miRs showed significant correlation with 3 out of 5 Wnt/ Ý-catenin pathway proteins. Conclusion: miR-10a, miR- 30e, miR-106b, miR-125b, miR-148a and miR-215 were highly associated with Wnt/ Ý-catenin pathway in HCC cases infected with HCV

Issued also as CD

There are no comments on this title.

to post a comment.

Click on an image to view it in the image viewer

Local cover image