Surgical management of sternal tumors in national cancer institute : Clinicopathological study of sternal tumors / Ayman Abdelhemeed Abdelrahman , Iman Loay Hussein

Thesis (M.Sc.) - Cairo University - National Cancer Institute - Department of Oncology-Surgical

Background: Sternal tumors should be considered malignant till proved otherwise. Wide resection with tumor free margins is required in order to provide the best chance for cure in both benign and malignant lesions. AIM: Our aim was to summarize our experience with the diagnosis, surgical treatment and evaluation of patients with sternal tumors. Methods: We collected and analyzed retrospective data on the clinical presentation, radiologic imaging, pathology and operative details of patients with sternal tumors whom underwent surgery at the National Cancer Institute between January 2005 and January 2015. Results: In all, 11of 21 patients were males, and the mean age of all patients was 40 years. The most common site within the sternum was the upper part of the body in 13 patients. All patients were followed-up for a median Follow up period for 31 months. Ranging from 2 to 124 months. Nineteen patients out of 21 diagnosed as a malignant lesion, so we have statistically studied them by overall survival in relation to different prognostic factors. We found that one year overall survival was 89.5 %, two and three year overall survival was, were 76.9 % and 69.2% respectively. We found that one year disease free survival was 84.2 %, two year disease free survival was 72.0%, and three year disease free survival was 64.8%. Twenty out of the 21 patients had rigid reconstruction after sternectomy to prevent flail chest, 14 of the 20 patients (70%) complicated by flail chest post operatively

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