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Screening for epidermal growth factor receptor mutations in lung cancer patients / Reham Ibrahim Saad ; Supervised Dina Mohammed Elabd , Mona Mohsen Abdelsalam , Sabah Ahmed Mohammed

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Reham Ibrahim Saad , 2017Description: 135 P. : facsimiles ; 25cmOther title:
  • الكشف عن طفرات مستقبلات عامل نمو البشرة فى مرضى سرطان الرئة [Added title page title]
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Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology Summary: There are two major classes of lung cancer, small cell carcinoma and non-small cell lung carcinoma. The non-small cell carcinoma is further subdivided into subtypes of which the main categories are adenocarcinoma and large cell carcinoma. Treatments include surgery, radiotherapy, and chemotherapy with varying degree of success. Epidermal growth factor receptor (EGFR) is a trans-membrane glycoprotein with an extra cellular epidermal growth factor binding domain and an intracellular tyrosine kinase domain that regulates signaling pathways to control cellular proliferation. The EGFR gene is located on chromosome 7p11.2 and is formed of 28 exons. The gene encodes a 170 kDa receptor tyrosine kinase formed 464aa. Mutations in epidermal growth factor receptor have been discovered in association with some lung cancers. Gene mutations in EGFR
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Item type Current library Home library Call number Copy number Status Date due Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.07.M.Sc.2017.Re.S (Browse shelf(Opens below)) Not for loan 01010110073788000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.07.M.Sc.2017.Re.S (Browse shelf(Opens below)) 73788.CD Not for loan 01020110073788000

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology

There are two major classes of lung cancer, small cell carcinoma and non-small cell lung carcinoma. The non-small cell carcinoma is further subdivided into subtypes of which the main categories are adenocarcinoma and large cell carcinoma. Treatments include surgery, radiotherapy, and chemotherapy with varying degree of success. Epidermal growth factor receptor (EGFR) is a trans-membrane glycoprotein with an extra cellular epidermal growth factor binding domain and an intracellular tyrosine kinase domain that regulates signaling pathways to control cellular proliferation. The EGFR gene is located on chromosome 7p11.2 and is formed of 28 exons. The gene encodes a 170 kDa receptor tyrosine kinase formed 464aa. Mutations in epidermal growth factor receptor have been discovered in association with some lung cancers. Gene mutations in EGFR

Issued also as CD

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