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Analytical study of some pharmaceutical nitrogenated cyclic compounds / Fatma Ahmed Shalaby ; Supervised Laila Elsayed Abdelfatah , Lories Ibrahim Bebawy , Ali Mohamed Yehia

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Fatma Ahmed Shalaby , 2017Description: 125 P. ; 25cmOther title:
  • دراسة تحليلية لبعض المركبات الصيدلية الحلقية المحتوية علي نيتروجين [Added title page title]
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  • Issued also as CD
Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Analytical Chemistry Summary: This work is concerned with stability indicating methods for determination of some drugs containing cyclic nitrogen including; zafirlukast (ZAF), aprepitant (APR). In this thesis different analytical techniques were adopted, namely, TLC-densitometric, spectrophotometric, spectrofluorimetric, chemometric, liquid chromatography, for the determination of the previously mentioned compounds in their pure powder, laboratory prepared mixtures and dosage forms. In part I; general introduction and literature review of ZAF and APR were described. In part II; different analytical methods were described for the determination of ZAF in presence of its alkaline degradates. Including; TLC-densitometry, second derivative (D2) spectrophotometry, specerofluorimetry, colorimetry. In part III; different analytical methods were described for the determination of APR in presence of its acid degradates. Including; TLC-densitometry, HPLC method, chemometry
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Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.08.03.M.Sc.2017.Fa.A (Browse shelf(Opens below)) Not for loan 01010110075500000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.08.03.M.Sc.2017.Fa.A (Browse shelf(Opens below)) 75500.CD Not for loan 01020110075500000

Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Analytical Chemistry

This work is concerned with stability indicating methods for determination of some drugs containing cyclic nitrogen including; zafirlukast (ZAF), aprepitant (APR). In this thesis different analytical techniques were adopted, namely, TLC-densitometric, spectrophotometric, spectrofluorimetric, chemometric, liquid chromatography, for the determination of the previously mentioned compounds in their pure powder, laboratory prepared mixtures and dosage forms. In part I; general introduction and literature review of ZAF and APR were described. In part II; different analytical methods were described for the determination of ZAF in presence of its alkaline degradates. Including; TLC-densitometry, second derivative (D2) spectrophotometry, specerofluorimetry, colorimetry. In part III; different analytical methods were described for the determination of APR in presence of its acid degradates. Including; TLC-densitometry, HPLC method, chemometry

Issued also as CD

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